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Quinapril
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About quinapril
| Type of medicine | Angiotensin converting enzyme (ACE) inhibitor |
| Used for | High blood pressure (hypertension) Heart failure |
| Also called | Accupro® Quinil® Accuretic® (quinapril with hydrochlorothiazide) |
| Available as | Tablets |
Quinapril works by causing blood vessels to relax, lowering blood pressure and increasing the supply of blood and oxygen to the heart. It can be used on its own or alongside other medicines which reduce blood pressure.
Before taking quinapril
Before taking quinapril make sure your doctor or pharmacist knows:
- If you are pregnant, trying for a baby or breast-feeding.
- If you have kidney, liver or heart disease.
- If you suffer from a collagen vascular disease, such as systemic lupus erythematosus (SLE) or scleroderma.
- If you are on a salt restricted diet or use salt substitutes which contain potassium.
- If you have cardiomyopathy (cardiac muscle disease) or aortic stenosis (narrowing of the blood vessel from the heart).
- If you have atherosclerosis (the build-up of fatty deposits on the walls of arteries).
- If you suffer from peripheral vascular disease (a particular type of poor circulation).
- If you have a history of angioedema (where the face, tongue and throat swell) or have ever had an allergic reaction to this or any other medicine.
- If you are having LDL apheresis (the removal of cholesterol from the blood by a machine).
- If you are having desensitisation treatment for bee and wasp stings.
- If you are having dialysis treatment.
- If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
- If you have ever had an allergic reaction to this or any other medicine.
How to take quinapril
- Before beginning treatment, read the manufacturer's printed information leaflet.
- Take quinapril exactly as directed by your doctor.
- Try to take quinapril at the same time each day to avoid missing any doses.
- If you forget to take a dose, skip the missed dose and take the next dose when it is due. Do not take two doses together to make up for a missed dose.
Getting the most from your treatment
- Keep your regular appointments with your doctor. You will probably need to have blood tests and blood pressure tests to ensure the dose you are taking is right for you.
- Try to avoid drinking too much alcohol as this will affect your blood pressure. If you do drink alcohol, drink only in moderation and be aware of its effects on you.
- Treatment with quinapril is usually life-long. Do not stop taking this medicine without speaking to your doctor first.
- If you are having any treatment like an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking.
- Do not stop taking this medicine without speaking to your doctor first.
- If you buy any medicines, check with a pharmacist that they are safe to take with your other medicines.
Can quinapril cause problems?
Along with their useful effects all medicines can cause unwanted side-effects which usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.
| Common side-effects - these affect less than 1 in 10 people who take this medicine | What can I do if I experience this |
| Light-headedness or dizziness when getting up from a sitting or lying position, especially the first time you take quinapril | Getting up slowly should help. If you begin to feel dizzy, lie down so that you do not faint, then sit for a few moments before standing. If this continues, speak with your doctor |
| Dry cough | If you develop a prolonged dry cough, contact your doctor. An alternative medicine may be available that does not cause this problem |
| Headache | Ask your pharmacist to recommend a suitable pain-killer. If the headache continues, speak with your doctor |
| Feeling or being sick | Eat little and often. Stick to simple foods |
| Stuffy or runny nose, tiredness or respiratory infections | Speak with your doctor if any of these are troublesome |
- If you experience swelling of the throat, tongue or face, go to the accident and emergency department of your local hospital immediately.
- If you experience chest pain, severe back pain, develop a severe sore throat, mouth ulcers, fever or jaundice (yellowing of the skin and whites of the eyes), speak with your doctor or go to your local accident and emergency department without delay.
If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.
How to store quinapril
- Keep all medicines out of the reach and sight of children.
- Store in a cool, dry place, away from direct heat and light.
Important information about all medicines
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References
- Manufacturer's PIL, Accupro® Tablets 5 mg, 10 mg, 20 mg and 40 mg, Pfizer Limited, electronic Medicines Compendium. Dated December 2008, accessed June 2009.
- British National Formulary; 57th Edition (March 2009) British Medical Association and Royal Pharmaceutical Society of Great Britain, London.
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The authors and editors of this article are employed to create accurate and up to date content reflecting reliable research evidence, guidance and best clinical practice. They are free from any commercial conflicts of interest. Find out more about updating.
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