Quinagolide

  • Take quinagolide tablets in the evening after food.
  • Quinagolide may cause dizziness, especially when getting up from a sitting or lying position. Getting up slowly should help.
  • Do not take quinagolide if you are pregnant. If you think you may have become pregnant while taking these tablets, see your doctor as soon as possible.
  • In rare cases some patients have experienced sudden onset of sleep with little or no warning of tiredness. If you experience this you should avoid driving, operating machinery or other tasks where you need to be fully alert. See your doctor as soon as possible.
Type of medicine Dopamine receptor stimulant
Used for Increased prolactin secretion
Also called Norprolac®
Available as Tablets

Quinagolide prevents the production of a chemical called prolactin. Prolactin is involved in many processes within the body, such as breast milk production and altering levels of hormones involved with controlling the menstrual cycle and fertility. Quinagolide is therefore helpful in reducing prolactin levels in order to reduce milk production for certain medical reasons, and to treat some types of infertility, breast problems and menstrual disorders.

Before taking quinagolide make sure your doctor or pharmacist knows:

  • If you are pregnant, trying for a baby or breast-feeding.
  • If you have problems with your liver or kidneys.
  • If you have hypotension (low blood pressure).
  • If you have ever suffered from psychosis (a mental health problem).
  • If you are taking other medicines, including those available to buy without a prescription, herbal and complementary medicines.
  • If you have ever had an allergic reaction to this or any other medicine.
  • Before starting this treatment, read the manufacturer's printed information leaflet from inside the pack.
  • Take quinagolide exactly as your doctor has told you and follow the printed instructions you have been given. Treatment usually begins with a 'starter pack' - this is so your dose can be increased slowly over a few days. Slowly increasing your dose like this will help reduce side-effects such as dizziness and low blood pressure.
  • Take your dose in the evening, with or soon after eating a meal or snack.
  • Keep your regular appointments with your doctor so your progress can be monitored. Your doctor will want to check your blood pressure, particularly at the start of this treatment.
  • Quinagolide should not be taken during pregnancy. If you think you may have become pregnant, see your doctor as soon as possible.
  • If you do not wish to become pregnant, discuss contraception with your doctor before taking quinagolide. Hormonal forms of contraception (such as 'the pill') are not suitable while you are taking these tablets.
  • In rare cases, some people taking quinagolide have experienced sudden onset of sleep with little or no warning of tiredness. If you experience this, you should see your doctor as soon as possible and avoid driving, operating machinery or other tasks where you need to be fully alert.
  • Quinagolide may cause dizziness, especially when getting up from a sitting or lying position. Getting up slowly should help.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. These usually improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.

Common side-effects What can I do if I experience this
Dizziness, tiredness, drowsiness Make sure your reactions are normal before driving, operating machinery or doing any other jobs which could be dangerous if you were not fully alert. Avoid alcohol as it will increase any feelings of drowsiness
Feeling or being sick, loss of appetite, abdominal pain Eat little and often. Stick to simple or bland foods and avoid rich, spicy foods. This usually passes as you get used to the medicine, but if it becomes troublesome, speak with your doctor who may prescribe you something to reduce the sickness
Headache Ask your pharmacist to recommend a suitable painkiller. If the headache continues, speak with your doctor
Diarrhoea Drink plenty of water to replace lost fluids
Constipation Try to eat a well balanced diet containing plenty of fibre and drink 6 - 8 glasses of water each day
Difficulty sleeping, swollen ankles, flushing, blocked nose If any of these become troublesome, speak with your doctor

Important: speak with your doctor if you notice any changes in behaviour such as a desire to gamble or an increased sex drive.

If you experience these, or any other worrying symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.

  • Keep all medicines out of the reach and sight of children.
  • Store in a cool, dry place, away from direct heat and light.

  • If you buy any medicines check with a pharmacist that they are safe to take with your other medicines.
  • Never take more than the prescribed dose. If you suspect that you or someone else has taken an overdose of this medicine go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
  • If you are having an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep out of date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.

Further reading & references

  • British National Formulary; 60th Edition (September 2010) British Medical Association and Royal Pharmaceutical Society of Great Britain, London.
  • Manufacturer's PIL, NorprolacĀ® Tablets; Manufacturer's PIL, NorprolacĀ® Tablets, Ferring Pharmaceuticals Ltd, electronic Medicines Compendium. Dated March 2010.
Original Author: Helen Allen Current Version:
Last Checked: 23/03/2011 Document ID: 1486  Version: 23 © EMIS

Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. EMIS has used all reasonable care in compiling the information but make no warranty as to its accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. For details see our conditions.

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