Piroxicam (topical)


  • This gel is for external use only.
  • Apply a thin layer and gently massage it into the affected area.
  • Wash your hands straight away after using this preparation.
  • Protect any treated areas from excessive sunlight as piroxicam may make your skin more sensitive to sunlight.
  • This preparation is not suitable for children under 12 years of age unless it is on the advice of a doctor.
Type of medicine Topical non-steroidal anti-inflammatory drug (NSAID)
Used for Treating pain and swelling due to strains and sprains, or arthritis in joints
Also called Feldene® gel
Available as Gel

Piroxicam is a non-steroidal anti-inflammatory drug (also known as an NSAID). It is used topically (applied directly onto the skin) to ease muscular pains, sprains, strains or arthritis pain in the hands or knees.

It works by being absorbed through the skin into the underlying tissues where it prevents the production of chemicals which cause pain and inflammation.

Before using topical piroxicam make sure your doctor or pharmacist knows:

  • If you are pregnant, trying for a baby or breast-feeding.
  • If you have ever had an unusual reaction after taking or using any other non-steroidal anti-inflammatory drug (NSAID) such as aspirin, diclofenac, ibuprofen or naproxen.
  • If you suffer from asthma or breathing problems.
  • If you have kidney or liver problems.
  • Before beginning treatment, read the manufacturer's printed information leaflet from inside the pack.
  • Apply a thin layer of gel and gently massage it into the affected area only. Wash your hands well afterwards.
  • Your doctor or pharmacist will recommend how often and for how long to use topical piroxicam, but this is usually 3 or 4 times a day and for no more than 4 weeks unless on your doctor's advice.
  • Do not use topical piroxicam near your eyes, inside your nose, or let it come into contact with any inflamed or broken skin.
  • Do not use this gel on any area that is covered by a bandage, dressing or sticking plaster.
  • If you forget to apply piroxicam at your usual time, apply it as soon as you remember.
  • Piroxicam may cause your skin to become more sensitive to sunlight during treatment. Do not use sunbeds, and protect any treated areas from strong sunlight.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. These usually improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.

Common side-effects - these affect less than 1 in 10 people who use this gel What can I do if I experience this
Itching or reddening of the skin at the site of application If this is severe, stop using topical piroxicam

If you experience any other symptoms which you think may be due to this gel, speak with your doctor or pharmacist.

  • Keep all medicines out of the reach and sight of children.
  • Store in a cool, dry place, away from direct heat and light.

  • Make sure that the person prescribing this medicine knows about any other medicines that you are taking or using. This includes medicines you buy and herbal and homeopathic medicines.
  • If you buy any medicines check with a pharmacist that they are safe to take with your other medicines.
  • If you suspect that someone has swallowed some of this gel, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.
  • If you are having an operation or any dental treatment, tell the person carrying out the treatment which medicines you are taking or using.
  • If you have any questions about this medicine ask your pharmacist.

Further reading & references

  • British National Formulary; 60th Edition (September 2010) British Medical Association and Royal Pharmaceutical Society of Great Britain, London.
  • Manufacturer’s PIL, Feldene® Gel; Manufacturer’s PIL, Feldene® Gel, Pfizer Limited, electronic Medicines Compendium. Dated October 2007.
Original Author: Helen Allen Current Version:
Last Checked: 23/03/2011 Document ID: 1190  Version: 23 © EMIS

Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. EMIS has used all reasonable care in compiling the information but make no warranty as to its accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. For details see our conditions.

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