About pipotiazine long-acting injection
|Type of medicine||Atypical antipsychotic|
|Used for||Easing the symptoms of schizophrenia and other similar mental health problems|
|Also called||Piportil® Depot|
|Available as||Long-acting depot injection|
Schizophrenia is a serious mental health condition that causes disordered ideas, beliefs and experiences. Pipotiazine palmitate is used to relieve the symptoms of schizophrenia and other similar mental health problems. Such symptoms include hearing, seeing, or sensing things that are not real, having mistaken beliefs, and feeling unusually suspicious.
Pipotiazine works by correcting the imbalance of chemical substances which act on the nervous system in your brain.
Long-acting or 'depot' injections are used once your symptoms have been eased by taking tablets or capsules. The injection slowly releases pipotiazine into your body and is given every four weeks. The main advantage of a depot injection is that you do not have to remember to take tablets every day.
Before using pipotiazine injection
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start having pipotiazine injections, it is important that your doctor knows:
- If you are pregnant, trying for a baby or breast-feeding.
- If you have a heart condition or blood vessel disease.
- If you have liver, kidney, or prostate problems.
- If you have a breathing problems.
- If you have thyroid problems.
- If you have any of the following: diabetes, epilepsy, Parkinson's disease, depression, glaucoma, or myasthenia gravis (this is a condition causing muscle weakness).
- If you have a condition called phaeochromocytoma (a tumour on your adrenal gland).
- If you have ever had jaundice (yellowing of your skin and the whites of your eyes), or a blood disorder.
- If you have ever had an allergic reaction to any medicine.
- If you are taking or using any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
How to use pipotiazine long-acting injection
- Before you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The leaflet will give you more information about pipotiazine, and a full list of possible side-effects from it.
- Pipotiazine injection will be given to you by your doctor or nurse. It is given by injection into the muscle of your buttock.
- If you haven't received an injection like pipotiazine before, a small dose is usually given as a test before you have a normal dose. This is to see how well you tolerate the injection.
- You may be asked to continue taking your current tablets or capsules for a short while after you have had your first injection. This is because it can take a few weeks before you feel the full effect of the injection.
- If you miss an appointment for an injection, you should contact your doctor's surgery to make another appointment as soon as possible. This is because the injection should be given to you without further delay.
Getting the most from your treatment
- Your treatment will require careful monitoring to make sure that you get the best possible benefit from pipotiazine. Keep your regular doctor's appointments so your progress can be checked.
- Pipotiazine may cause your skin to become more sensitive to sunlight than normal. Use a sunscreen that protects against UVA light and has a sun protection factor (SPF) of at least 15, especially in strong sunlight or until you know how your skin reacts. Do not use sunbeds.
- If you are having any dental treatment or an operation, tell the person carrying out the treatment which medicines you are taking. This is important because pipotiazine may interfere with any anaesthetic you receive.
- If you buy or take any 'over-the-counter' medicines, check with a pharmacist that they are safe to take with pipotiazine.
- If you drink alcohol, ask your doctor for advice about drinking while you are on pipotiazine. Alcohol may increase the chance that you experience side-effects and may not be recommended for you.
- If you have diabetes you may need to check your blood glucose more frequently, as pipotiazine may affect the levels of sugar in your blood. Your doctor will be able to advise you about this.
Can pipotiazine depot injection cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. These usually improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.
|Common pipotiazine side-effects||What can I do if I experience this?|
|Pain and redness at the site of the injection||This should quickly pass. If the area becomes swollen or 'lumpy', let your doctor know|
|Feeling dizzy or sleepy, blurred vision||If this happens, do not drive or use tools or machines. Do not drink alcohol as it will increase these effects|
|Feeling light-headed or dizzy when you stand up||Getting up more slowly may help. If you begin to feel dizzy, lie down so that you do not faint|
|Dry mouth, difficulty sleeping, blocked nose, feeling agitated, increased weight, changes in your heartbeat or rhythm||Discuss these with your doctor if any become troublesome|
Important: if you experience 'flu-like' symptoms including muscle stiffness, with a high temperature, confusion, a fast heartbeat and sweating, contact your doctor immediately. These may be signs of a rare but serious condition known as neuroleptic malignant syndrome.
Important: if you experience abnormal face or body movements, restlessness, or any involuntary muscle movements, discuss these with your doctor as soon as possible.
If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.
How to store pipotiazine depot injection
- Keep all medicines out of the reach and sight of children.
- Store in a cool, dry place, away from direct heat and light.
Important information about all medicines
Further reading & references
- British National Formulary; 63rd Edition (Mar 2012) British Medical Association and Royal Pharmaceutical Society of Great Britain, London
- Manufacturer's PIL, Piportil® Injection,; Manufacturer's PIL, Piportil® Injection, sanofi-aventis, The electronic Medicines Compendium. Dated October 2011.
|Original Author: Helen Allen||Current Version: Helen Allen||Peer Reviewer: Dr Adrian Bonsall|
|Last Checked: 19/07/2012||Document ID: 3837 Version: 24||© EMIS|
Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. EMIS has used all reasonable care in compiling the information but make no warranty as to its accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. For details see our conditions.