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Pilocarpine eye preparations

  • Headache can be a troublesome side-effect when you first start using pilocarpine. Ask your pharmacist to recommend a suitable pain-killer.
  • Keep your regular appointments with your doctor or clinic so that your progress can be checked.
  • Do not wear soft contact lenses whilst you are using pilocarpine.

About pilocarpine eye preparations

Type of medicineMiotic
Used forGlaucoma (increased pressure in the eye)
Also calledPilocarpine hydrochloride
Minims® Pilocarpine
Pilogel®
Available asEye drops, single-use eye drops and preservative-free eye drops
Ophthalmic gel

Glaucoma is caused by a blockage in the eye which prevents fluid from leaving the eye. This causes the pressure within the eye to build up, causing pain and discomfort. Pilocarpine works by opening up the drainage channels in the eye, allowing fluid to leave the eye and so relieving pressure.

Before using pilocarpine eye preparations

Before using pilocarpine eye preparations make sure your doctor or pharmacist knows:

  • If you are pregnant, trying for a baby or breast-feeding.
  • If you have heart problems or hypertension (high blood pressure).
  • If you have asthma.
  • If you have a stomach ulcer.
  • If you have Parkinson's disease.
  • If you have been experiencing difficulty urinating (passing water).
  • If you have any other eye problems.
  • If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
  • If you have ever had an allergic reaction to this or any other medicine.

How to use pilocarpine eye preparations

  • Before beginning treatment, read the manufacturer's printed information leaflet.
  • Use pilocarpine exactly as directed by your doctor. The eye drops can be used up to four times a day but your doctor will tell you the dose that is right for you. The ophthalmic gel is to be used once a day at bedtime.

Using pilocarpine eye drops:

  1. Wash your hands well before use.
  2. Remove the outer cap.
  3. Tilt the head back and pull the lower lid of the eye out to form a pocket.
  4. Hold the container between the thumb and middle finger of the other hand and turn the container upside down near to the eye. Try not to touch the eye with the nozzle.
  5. Apply enough pressure to the container to release one to two drops.
  6. Close the eye and keep the eye closed for a minute or two. If you think that you have missed the eye, then insert another drop.
  7. Repeat in the other eye if you have been instructed to use pilocarpine in both eyes.
  8. Replace the outer cap on the container. Try not to touch the applicator tip with any surface (including your eye or fingers).
  9. Wash your hands again.

Using pilocarpine eye gel:

  1. Wash your hands well before use.
  2. Remove the outer cap.
  3. Tilt the head back and pull the lower lid of the eye out to form a pocket.
  4. Hold the container between the thumb and middle finger of the other hand and turn the container upside down near to the eye. Try not to touch the eye with the nozzle.
  5. Apply enough pressure to the container to release a line of gel (1-1.5 cm long) along the inside of the lower lid.
  6. Close the eye and blink for a short while to spread the gel around the inside of the eye.
  7. Repeat in the other eye if you have been instructed to use pilocarpine in both eyes.
  8. Replace the outer cap on the container. Try not to touch the applicator tip with any surface (including your eye or fingers).
  9. Wash your hands again.

Getting the most from your treatment

  • If you are using other eye drops or ointments, leave at least five minutes between using each one.
  • Try to use this preparation at regular intervals as directed by your doctor and try not to miss any doses.
  • Keep your regular appointments with your doctor so that your progress can be checked.
  • Do not wear soft contact lenses while you are being treated with pilocarpine.

Can pilocarpine eye preparations cause problems?

Along with their useful effects all medicines can cause unwanted side effects which usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side effects continue or become troublesome.

Common side-effects - these affect less than 1 in 10 people who use this preparationWhat can I do if I experience this
HeadacheThis can be troublesome at the start of treatment. Ask your pharmacist to recommend a suitable pain-killer
Blurred vision and difficulty seeing in poor lightingMake sure you can see clearly before driving or doing other jobs which would be dangerous if you were not able to see clearly
Burning, itching, smarting of the eyesThis should not last long

If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.

How to store pilocarpine eye preparations

  • Keep all medicines out of the reach and sight of children.
  • Once the container has been opened it may be used for up to 4 weeks only. After this time you will need a fresh supply. If you are using a single use vial, throw the vial away after using.
  • Store in a cool, dry place, away from direct heat and light.

Important information about all medicines


  • If you are having any treatment like an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking.
  • Never take more than the prescribed dose. If you suspect that you or someone else has swallowed some of this medicine, go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep out of date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.

References

  • Manufacturer's PIL, Pilogel®, Alcon Laboratories (U.K) Limited, electronic Medicines Compendium. Dated January 2000, accessed April 2009.
  • British National Formulary; 57th Edition (March 2009) British Medical Association and Royal Pharmaceutical Society of Great Britain, London (link to current BNF).
Comprehensive patient resources are available at www.patient.co.uk
© EMIS 2009DocID: 3290DocRef: dils2217Last Reviewed: 12 May 2009Version: 22
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