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Paracetamol and metoclopramide
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About paracetamol and metoclopramide
| Type of medicine | Antimigraine |
| Used for | Migraine |
| Also called | Paramax® |
| Available as | Tablets and sachets |
About paracetamol and metoclopramide
This is a combination medicine containing paracetamol and metoclopramide. It is used to relieve the symptoms of migraine including headache, nausea (feeling sick) and vomiting (being sick).
Paracetamol belongs to the group of medicines known as analgesics or painkillers. It helps to ease the pain of the migraine headache.
Metoclopramide belongs to the group of medicines known as anti-emetics which relieve the symptoms of nausea and vomiting. It reduces sickness by increasing the contractions of the stomach and intestines. This action also helps quicken the absorption of the painkilling paracetamol.
Before taking paracetamol and metoclopramide
Before taking paracetamol and metoclopramide make sure your doctor or pharmacist knows:
- If you are under 12 years of age.
- If you are pregnant, trying for a baby or breast-feeding.
- If you suffer from liver or kidney problems.
- If you are an alcoholic or drink a lot of alcohol.
- If you suffer from epilepsy.
- If you are so constipated that you feel there may be a blockage.
- If you have had surgery on your stomach or bowels within the last four days.
- If you have noticed that your stools are blackened or if there is blood present.
- If you have allergies or have asthma.
- If you have porphyria (a blood disorder).
- If you suffer from phaeochromocytoma (a growth affecting the adrenal glands).
- If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
- If you have ever had a reaction to either paracetamol or metoclopramide, or any other medicine.
How to take paracetamol and metoclopramide
- Before beginning treatment, read the manufacturer's printed information leaflet.
- Take your medication exactly as directed by your doctor.
- If you are over 20 years of age: take two sachets or two tablets at the beginning of a migraine attack. A further two sachets or two tablets can be taken every four hours if required, but do not take more than six sachets or six tablets in any 24 hour period.
- If you are between 12 and 20 years of age: take one sachet or one tablet at the beginning of a migraine attack. A further one sachet or one tablet can be taken every four hours if required, but do not take more than three sachets or tablets in any 24 hour period.
- If you have been supplied the sachets, dissolve the powder from the sachet(s) in a quarter of a glassful of water before swallowing.
Getting the most from your treatment
- This preparation can cause drowsiness. Make sure you know how you react to this medicine before driving, operating machinery or doing any other jobs which could be dangerous if you were not fully alert.
- Do not take any other medicines containing paracetamol at the same time as this medicine. Remember many common over the counter preparations also contain paracetamol. Always read the label or ask your pharmacist.
- If you are having any treatment like an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking.
Can paracetamol and metoclopramide cause problems?
Along with their useful effects, all medicines can cause unwanted side effects which usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side effects continue or become troublesome.
| Common side-effects - these affect less than 1 in 10 people who take this medicine | What can I do if I experience this |
| Drowsiness | Make sure your reactions are normal before driving, operating machinery, or doing any other jobs which could be dangerous if you were not fully alert |
| Diarrhoea | Drink plenty of water to replace lost fluid |
| Dizziness, light-headedness | Moving and getting up slowly should help. |
| Breast changes, loss of menstrual periods, mood changes, weakness or skin rash | Discuss these with your doctor |
If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.
How to store paracetamol and metoclopramide
- Keep all medicines out of the reach and sight of children.
- Store in a cool, dry place, away from direct heat and light.
Important information about all medicines
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References
- Manufacturer's PIL, Paramax® Tablets, Sanofi-aventis, electronic Medicines Compendium. Revised August 2007, accessed February 2009.
- Manufacturer's PIL, Paramax® Effervescent Powder, Sanofi-aventis, electronic Medicines Compendium. Revised August 2007, accessed February 2009.
- British National Formulary; 56th Edition (September 2008) British Medical Association and Royal Pharmaceutical Society of Great Britain, London.
The authors and editors of this article are employed to create accurate and up to date content reflecting reliable research evidence, guidance and best clinical practice. They are free from any commercial conflicts of interest. Find out more about updating.
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