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Oseltamivir

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  • Oseltamivir is used to prevent and treat influenza virus A and B infections.
  • Follow the dosing instructions carefully and remember to take the complete course.
  • You can help prevent the virus from spreading to others by using clean tissues to cover your mouth and nose when coughing and sneezing, carefully disposing of tissues after each use and washing your hands regularly.
  • Remember to keep warm, drink plenty of fluids and stay away from crowds.

About oseltamivir

Type of medicine Antiviral
Used for Treating or preventing influenza (flu).
Also called Tamiflu®
Available as Capsules and oral suspension

Oseltamivir works by preventing influenza viruses A and B from spreading inside the body. By doing this it reduces or prevents the symptoms of the influenza virus infection. As well as relieving the symptoms of flu, it also shortens the time of illness by around one day and reduces the risk of other problems that can occur alongside flu, such as pneumonia.

It is most effective in reducing the symptoms of flu if it is started within a few hours of the first symptoms of the infection. It can however be started up to 48 hours after the start of the infection.

It is also used to prevent flu when there are high levels of influenza in the community such as in epidemics and pandemics. It is useful for those who have been in close contact with people suffering from influenza at these times, or those who would be at particular risk if they developed flu.

Oseltamivir is not a substitute for seasonal flu vaccination.

Before taking oseltamivir

Before taking oseltamivir make sure your doctor or pharmacist knows:

  • If you are pregnant, trying for a baby or breast-feeding.
  • If you have kidney problems.
  • If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
  • If you have ever had an allergic reaction to this or any other medicine.

How to take oseltamivir

  • Before beginning treatment, read the manufacturer's printed information leaflet.
  • Take oseltamivir exactly as directed by your doctor. Follow the dosing instructions on the pack carefully.
  • Oseltamivir is a course of treatment which usually lasts 5-10 days although it may sometimes be taken for longer periods. Remember to complete the whole course (even if you do not feel unwell), otherwise the symptoms may return.
  • Take oseltamivir with a drink of water. You can take it with or without food, although it is recommended to take it with food to reduce the chance of feeling or being sick.
  • Try to take oseltamivir at the same times each day to avoid missing any doses.
  • If you forget to take a dose, take one as soon as you remember unless it is time for your next dose in which case skip the missed dose. Do not take two doses at the same time to make up.

How to measure the correct amount of suspension if you or your child has been given the oral suspension:

  1. Shake the bottle well before using.
  2. Push the plunger of the oral dispenser fully down to the tip.
  3. Remove the cap from the bottle of oral suspension.
  4. Insert the tip of the dispenser into the bottle adapter.
  5. Turn the bottle (with the dispenser attached) upside down.
  6. Slowly pull out the plunger of the dispenser to the graduation which marks the dose you need.
  7. Turn the bottle (with the dispenser attached) upright.
  8. Slowly remove the dispenser from the bottle.
  9. Push the suspension directly into your (or your child's) mouth by pushing down the plunger of the dispenser and then swallow the medicine.
  10. Immediately after administration, take the dispenser apart and rinse both parts of the dispenser under running tap water.

Getting the most from your treatment

  • If your influenza symptoms get worse or the fever continues, speak with your doctor.
  • To stop the spread of flu to others it is important to follow good hygiene practices. Remember to use clean tissues to cover your mouth and nose when you cough and sneeze, bin the tissues after use and regularly wash your hands with soap and hot water.

Can oseltamivir cause problems?

Along with their useful effects all medicines can cause unwanted side effects which usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side effects continue or become troublesome.

Common side-effects - these affect less than 1 in 10 people who take this medicine What can I do if I experience this
Feeling or being sick, tummy pain Eat little and often and stick to simple foods
Diarrhoea Stick to simple foods and drink plenty of water to replace any lost fluids
Headache Ask your pharmacist to recommend a suitable pain-killer
Conjunctivitis This should clear up within a day or so. Speak to your doctor, optician or pharmacist if you are concerned

If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.

How to store oseltamivir

  • Keep all medicines out of the reach and sight of children.
  • The oral suspension (when reconstituted) can be stored for 10 days at room temperature or 17 days if it is refrigerated. Do not use the suspension after this time.
  • Store in a cool, dry place, away from direct heat and light.

Important information about all medicines


  • If you are having any treatment like an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking.
  • If you buy any medicines, check with a pharmacist that they are safe to take with your other medicines.
  • Never take more than the prescribed dose. If you suspect that you or someone else has taken an overdose of this medicine, go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep out of date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.

References

Comprehensive patient resources are available at www.patient.co.uk
© EMIS 2009 DocID: 12254 DocRef: dils3948 Last Reviewed: 18 May 2009 Version: 1

The authors and editors of this article are employed to create accurate and up to date content reflecting reliable research evidence, guidance and best clinical practice. They are free from any commercial conflicts of interest. Find out more about updating.

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