Norfloxacin

  • Norfloxacin is used for urinary tract infections.
  • It is important to complete the course you have been given unless you are told to stop. This is to prevent the infection from coming back.
  • The most common side-effects are feeling sick, diarrhoea, dizziness and headache.
  • Norfloxacin may impair your alertness, so make sure your reactions are normal before driving or operating machinery.
Type of medicine Quinolone antibiotic
Used for Urinary infections such as cystitis
Also called Utinor®
Available as Tablets

Norfloxacin is used to treat bacterial infections of the urinary system in adults. It works by killing the bacteria which cause the infection.

Before taking norfloxacin make sure your doctor or pharmacist knows:

  • If you are pregnant, trying for a baby or breast-feeding.
  • If you have kidney problems.
  • If you have epilepsy or any other condition that causes convulsions.
  • If you have myasthenia gravis (a muscle weakening disease).
  • If you have glucose 6-phosphate dehydrogenase (G6PD) deficiency.
  • If you are taking other medicines, including those available to buy without a prescription, herbal and complementary medicines.
  • If you have ever had an allergic reaction to this or any other medicine.
  • Before starting this treatment, read the manufacturer's printed information leaflet from inside the pack.
  • Take norfloxacin exactly as your doctor has told you.
  • Norfloxacin should be taken when your stomach is empty. This means you should take your doses an hour before food or 2 hours after food.
  • Spread your doses out evenly throughout the day.
  • Keep taking this antibiotic until the course is finished unless you are told to stop. This is important in order to prevent the infection from coming back.
  • Do not take indigestion remedies, or medicines containing iron or zinc, in the 2 hours before or after you take norfloxacin.
  • If you forget to take a dose, take it as soon as you remember and then continue as before. Do not take two doses together to make up for a forgotten dose.
  • If you are using oral combined hormonal contraception (the 'pill'), additional contraceptive precautions such as condoms are not required during a course of this antibiotic unless you are sick or have diarrhoea. If you need further advice, speak with your doctor or pharmacist.
  • If you buy any medicines, particularly anti-inflammatory painkillers, check with a pharmacist that they are safe to take with this antibiotic.
  • Norfloxacin may cause your skin to become more sensitive to sunlight than normal. Protect your skin particularly if you are exposed to strong sunlight for long periods during the day. Do not use sunbeds.
  • Norfloxacin may impair your ability to concentrate. Make sure your reactions are normal before driving, operating machinery or doing other jobs which could be dangerous if you were not sufficiently alert.
  • If you have diabetes, you may need to check your blood glucose levels more regularly as norfloxacin may affect the levels of sugar in your blood.
  • If you still feel unwell after completing your course of this antibiotic, make another appointment to see your doctor.
  • Some people develop thrush (redness and itching in the mouth or vagina) after taking a course of antibiotics. If you think you have thrush, speak with your doctor or pharmacist for advice.
  • This antibiotic may stop the oral typhoid vaccine from working. If you are having any vaccinations, make sure the person treating you knows that you are taking this medicine.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. These usually improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.

Common side-effects - these affect less than 1 in 10 people who take this medicine What can I do if I experience this
Feeling or being sick, indigestion, abdominal pain, and wind Eat little and often. Stick to simple or bland foods
Diarrhoea Drink plenty of water to replace lost fluids. If the diarrhoea is severe or continues to be a problem, speak with your pharmacist or doctor
Headache Ask your pharmacist to recommend a suitable painkiller. If the headache continues, speak with your doctor
Dizziness If affected, do not drive or operate machinery

Important: If you develop any of the following rare symptoms, contact your doctor for advice straight away:

  • Swelling of your tongue, mouth, or face, or any problems with your breathing.
  • A severe rash.
  • Pain or inflammation in your joints (particularly in your hips, knees or ankles).

If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist for advice.

  • Keep all medicines out of the reach and sight of children.
  • Store in a cool, dry place, away from direct heat and light.

  • Never take more than the prescribed dose. If you suspect that you or someone else has taken an overdose of this medicine go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
  • If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking this medicine.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep out of date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.

Further reading & references

  • British National Formulary; 62nd Edition (Sep 2011) British Medical Association and Royal Pharmaceutical Society of Great Britain, London
  • Manufacturer's PIL, UtinorĀ® 400mg Tablets; Manufacturer's PIL, UtinorĀ® 400mg Tablets, Merck Sharp & Dohme Limited, electronic Medicines Compendium. Dated March 2009.
Original Author: Helen Allen Current Version:
Last Checked: 07/06/2011 Document ID: 4133  Version: 24 © EMIS

Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. EMIS has used all reasonable care in compiling the information but make no warranty as to its accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. For details see our conditions.

The Information Standard - certified member

The authors and editors of this article create up to date content reflecting reliable research evidence, guidance and best clinical practice. Learn more

Advertisements