Nitrazepam

  • Nitrazepam is for the short-term relief of sleeplessness.
  • It can cause drowsiness and light-headedness which can last into the next day.
  • Do not drink alcohol while you are being treated with nitrazepam.
Type of medicine Benzodiazepine
Used for Insomnia (difficulty sleeping)
Available as Tablets and oral liquid

Nitrazepam is used to treat insomnia (difficulty sleeping), but only for a short period of time.

It works by affecting the part of the brain that controls emotion and also by relaxing muscles. This reduces anxiety and promotes sleepiness.

Before taking nitrazepam make sure your doctor or pharmacist knows:

  • If you are pregnant, trying for a baby or breast-feeding.
  • If you have any breathing problems.
  • If you have sleep apnoea syndrome (short periods in your sleep where you stop breathing).
  • If you have liver or kidney problems.
  • If you have depression or any other mental health problem.
  • If you have myasthenia gravis (a muscle weakening disease) or any other muscle weakness.
  • If you have porphyria (a rare blood disorder).
  • If you have ever had an addiction to alcohol or drugs.
  • If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
  • If you have ever had an allergic reaction to this or to any other medicine.
  • Before beginning treatment, read the manufacturer's printed information leaflet.
  • Take nitrazepam exactly as directed by your doctor.
  • Nitrazepam is usually taken just before bedtime.
  • Nitrazepam is to be taken for short periods of time only, from a few days up to 3 weeks. It should not be taken for longer periods of time, as this may lead to your feeling dependent on it. If you have already been taking nitrazepam for longer than 3 weeks, check with your doctor before stopping taking it. It must be stopped gradually as stopping suddenly can cause unpleasant withdrawal symptoms such as anxiety, tremor and sleeplessness.
  • Do not drink alcohol while you are taking nitrazepam. It will increase side-effects such as drowsiness.
  • If you buy any medicines while you are taking nitrazepam, check with a pharmacist that they are safe to take together.
  • If you are having any treatment like an operation or dental treatment, tell the person carrying out the treatment that you are taking nitrazepam.

Along with their useful effects, all medicines can cause unwanted side-effects although not everyone experiences them. These usually improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.

Common side-effects - these affect less than 1 in 10 people who take this medicine What can I do if I experience this
Drowsiness, dizziness, feeling light-headed or less alert than normal Make sure your reactions are normal before driving, operating machinery or doing any other jobs which could be dangerous if you were not fully alert. Do not drink alcohol
Unsteadiness or muscle weakness, confusion, forgetfulness Let your doctor know if these are troublesome
Headache Ask your pharmacist to recommend a suitable painkiller. If the headache continues, let your doctor know

If you experience any other symptoms which you think may be due to this medicine, discuss them with your doctor or pharmacist.

  • Keep all medicines out of the reach and sight of children.
  • Store in a cool, dry place, away from direct heat and light.

  • Never take more than the prescribed dose. If you suspect that you or someone else has taken an overdose of this medicine go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
  • Always read the printed information leaflet that comes with your medicine.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.

Further reading & references

  • British National Formulary; 59th Edition (March 2010) British Medical Association and Royal Pharmaceutical Society of Great Britain, London.
  • Manufacturer's PIL, Nitrazepam Tablets 5 mg, Actavis UK Ltd, electronic Medicines Compendium. Dated October 2008.
Original Author: Helen Allen Current Version:
Last Checked: 21/10/2010 Document ID: 1430  Version: 23 © EMIS

Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. EMIS has used all reasonable care in compiling the information but make no warranty as to its accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. For details see our conditions.

The Information Standard - certified member

The authors and editors of this article create up to date content reflecting reliable research evidence, guidance and best clinical practice. Learn more

Advertisements