Before taking naproxen

Before taking naproxen make sure your doctor or pharmacist knows:

• If you are pregnant, trying for a baby or breast-feeding.
• If you are over 65 years of age.
• If you have liver or kidney problems.
• If you have asthma or any other allergic disorder.
• If you have ever had a stomach or duodenal ulcer.
• If you have heart problems.
• If you have ever had blood clotting problems.
• If you have blood in your stools.
• If you have systemic lupus erythematosus (an inflammatory condition also called lupus or SLE).
• If you are taking other medicines, including those available to buy without a prescription, herbal and complementary medicines.
• If you have ever had an allergic or unusual reaction to any other NSAID (this includes aspirin, ibuprofen, diclofenac and indometacin) or to any other medicine.

How to take naproxen

• Before starting naproxen, read the manufacturer's printed information leaflet from inside the pack.
• Take naproxen exactly as your doctor has told you.
• Taking naproxen with a glass of milk or after eating some food may help prevent side-effects such as indigestion. However, if you have been given Vimovo® tablets, these should be taken before meals.
• If you have been given enteric coated tablets (such as Naprosyn® EC), these should be swallowed whole and not chewed. Do not take indigestion remedies at the same time as enteric coated tablets as these will stop the protective coating from working as it should.
• If you have been given modified-release tablets (Vimovo®), these should be swallowed whole, and taken at least 30 minutes before a meal.
• If you forget to take a dose, take it as soon as you remember unless it is nearly time for your next dose, in which case leave out the missed dose. Do not take two doses together to make up for a missed dose.

Getting the most from your treatment

• Keep any regular doctor's appointments so your progress can be monitored.
• Your doctor will try to prescribe you the lowest dose for the shortest time so that you do not suffer from side-effects. If you need to take naproxen for a long time, your doctor may want to prescribe another medicine along with it to protect your stomach from irritation.
• If you buy any medicines, check with a pharmacist that they are safe to take with naproxen.

Can naproxen cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. These usually improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.

• Any sign of bleeding in the stomach or intestine, such as blood in vomit or dark stools.
• Any shortness of breath, or swelling of the mouth or face.
• A severe skin rash.
• A severe headache with a high temperature and a stiff neck.

If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.

How to store naproxen

• Keep all medicines out of the reach and sight of children.
• Store in a cool, dry place, away from direct heat and light.

Important information about all medicines

References

• Manufacturer’s PIL, Naprosyn® 250mg and 500mg Tablets, Roche Products Limited, electronic Medicines Compendium. Dated December 2009.
• Manufacturer’s PIL, Synflex® 275mg Tablets, Roche Products Limited, electronic Medicines Compendium. Dated December 2009.
• Manufacturer’s PIL, Napratec® OP, Pharmacia Limited, electronic Medicines Compendium. Dated January 2011.
• Manufacturer’s PIL, Vimovo® 500 mg/20 mg modified-release tablets, AstraZeneca UK Limited, electronic Medicines Compendium. Dated October 2010.
• British National Formulary; 60th Edition (September 2010) British Medical Association and Royal Pharmaceutical Society of Great Britain, London.