Moclobemide

About moclobemide

Moclobemide works by reducing the action of an enzyme in the brain called monoamine oxidase A. This can help people with some types of depression.

Before taking moclobemide

Before taking moclobemide make sure your doctor or pharmacist knows:

• If you are pregnant, trying for a baby or breast-feeding.
• If you suffer from hyperthyroidism (an overactive thyroid gland) or phaeochromocytoma (a growth on the adrenal glands).
• If you suffer from liver problems.
• If you have recently stopped taking any other medicines to treat your depression.
• If you suffer from bipolar disorder, schizophrenia or are feeling particularly agitated or confused.
• If you have ever had an allergic reaction to this or any other medicine.
• If you are taking any other medicines, including those available to buy without a prescription, herbal and complementary medicines.

How to take moclobemide

• Always read the manufacturer’s information leaflet, if possible, before beginning treatment.
• Take moclobemide immediately after a meal.
• Try to take moclobemide at the same times each day to avoid missing any doses. If you do miss a dose, take one as soon as you remember unless its time for your next dose. Never take two doses together.
• Do not stop taking this medicine without speaking to your doctor first.
• Never take more than the prescribed dose. If you suspect that you or someone else has taken an overdose of moclobemide contact your doctor or go to the accident and emergency department of your local hospital at once. Take the container with you even if it is empty.

Getting the most from your treatment

• Keep your regular appointment with your doctor so your progress can be checked.
• A special diet does not need to be followed when taking moclobemide. However some people who take moclobemide may be very sensitive to a substance called tyramine in foods. Therefore you should avoid eating large amounts of food which contain tyramine such as mature cheese, yeast extracts (e.g. Marmite®) or fermented soya products (an ingredient in some Chinese food).
• You may have to take moclobemide for several weeks before you feel the full effect.
• Tell your doctor if you are having thoughts of harming yourself.
• Before having any surgery including, dental or emergency treatment tell the surgeon, doctor or dentist that you are taking moclobemide.
• Check with your pharmacist before buying or taking any medicines to make sure that they are safe to take with moclobemide. Some commonly used cough and cold remedies should not be used with moclobemide.

Can moclobemide cause problems

Along with their useful effects all medicines can cause unwanted side effects, which usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side effects continue or become troublesome.

Other possible side effects include problems sleeping, feeling anxious, restless or irritable, a numb or tingling feeling, swelling, confusion, skin rash, itching, flushing, convulsions.

If you experience any other worrying symptoms that you think may be due to this medicine speak to your doctor or pharmacist for advice.

How to store moclobemide

• Keep all medicines out of the reach of children.
• Store in a cool, dry place, away from direct heat and light.

Important information about all medicines