Misoprostol

About misoprostol

Misoprostol works by being similar to substances (called prostaglandins) that your body makes in the stomach and intestine. These prostaglandins help to protect the lining of the stomach.
Misoprostol may help prevent you getting ulcers in your stomach or the part it empties into (called the duodenum). These ulcers could be caused by taking non-steroidal anti-inflammatory drugs (NSAIDs) like diclofenac and naproxen. NSAIDs may reduce the natural amount of prostaglandins in your stomach and intestine. This can cause indigestion and lead to ulcers forming. The misoprostol tablets will replace these prostaglandins and help to protect your stomach and intestine, so you can continue getting benefit from your NSAID.

Before taking misoprostol

Before taking misoprostol make sure your doctor or pharmacist knows:

• If you are pregnant, trying for a baby or breast-feeding.
• If you have low or high blood pressure, or any disease of the blood vessels or heart.
• If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
• If you have ever had an allergic reaction to this or any other medicine.

How to take misoprostol

• Before beginning treatment, read the manufacturer's printed information leaflet.
• Take your medication exactly as directed by your doctor.
• Try to take misoprostol at the same times each day to avoid missing any doses.
• If you forget to take a dose, take one as soon as you remember unless it is nearly time for your next dose. Do not take two doses at the same time to make up. If in doubt, speak to your pharmacist or doctor.

Getting the most from your treatment

• Take each dose with or immediately after food.
• Do not take antacid indigestion remedies at the same time of day as misoprostol. Take indigestion remedies at least two hours before or two hours after a dose of misoprostol.
• It is very important that women do not become pregnant whilst being treated with misoprostol. If you are a woman of childbearing age you must take effective contraceptive measures. Ask your doctor if you are unsure.
• If you are having any treatment like an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking.
• Keep your regular doctor's appointment so your progress can be monitored.
• Do not stop taking this medicine without speaking to your doctor first.
• If you buy any medicines, check with a pharmacist that they are safe to take with your other medicines.

Can misoprostol cause problems?

Along with their useful effects all medicines can cause unwanted side effects, which usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side effects continue or become troublesome.

If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.

How to store misoprostol

• Keep all medicines out of the reach and sight of children.
• Store in a cool, dry place, away from direct heat and light.

Important information about all medicines