Before taking metronidazole

Before taking metronidazole make sure your doctor or pharmacist knows:

• If you have liver problems or are on kidney dialysis.
• If you are pregnant, trying for a baby or breast-feeding.
• If you have a dependency on alcohol.
• If you suffer from the rare blood disorder called porphyria.
• If you are taking other medicines, including those available to buy without a prescription, herbal and complementary medicines.
• If you have ever had an allergic reaction to this or any other medicine.

How to take metronidazole

• Before starting this treatment, read the manufacturer's printed information leaflet.
• Take metronidazole exactly as directed by your doctor or dentist.
• You must take metronidazole at regular intervals and complete the course you have been given, even if you feel well.
• Take the tablets with a glass of water, with or just after food. Swallow the tablets whole - do not crush or chew them.
• If you forget to take a dose, take it as soon as you remember unless it is nearly time for your next dose, in which case leave out the missed dose. Do not take two doses together to make up for a missed dose.

1. Remove the suppository from the wrapping.
2. You may find that inserting the suppository is easier if you squat or bend forward.
3. Using your finger gently push the suppository into your rectum (back passage) as far as possible, pointed end first.
4. Remain still for a little while to help you to hold the suppository in place.
5. Wash you hands after use.

Getting the most from your treatment

• Important: Do not drink alcohol while you are being treated with metronidazole and for 48 hours after finishing your course of treatment. This is because drinking alcohol with metronidazole may make you feel very sick and cause other unpleasant effects.
• If you buy any medicines, check with a pharmacist that they are safe to take with metronidazole. Some cough and cold preparations contain alcohol and should not be taken with metronidazole.
• If you are taking metronidazole for longer than 10 days, you may need to have some tests. Make sure you keep any doctor's appointments that you have been given.

Can metronidazole cause problems?

Along with their useful effects, all medicines can cause unwanted side-effects although not everyone experiences them. These usually improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.

If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.

How to store metronidazole

• Keep all medicines out of the reach and sight of children.
• Store in a cool, dry place, away from direct heat and light.

Important information about all medicines

References

• Manufacturer's PIL, Flagyl® 200mg and 400mg Tablets, Winthrop Pharmaceuticals UK Ltd, electronic Medicines Compendium. Dated May 2009, accessed November 2010.
• Manufacturer's PIL, Flagyl® S Suspension, Winthrop Pharmaceuticals UK Ltd, electronic Medicines Compendium. Dated December 2009, accessed November 2010.
• Manufacturer's PIL, Flagyl® Suppositories 500 mg and 1.0 g, Winthrop Pharmaceuticals UK Ltd, electronic Medicines Compendium. Dated June 2008, accessed November 2010
• British National Formulary; 60th Edition (September 2010) British Medical Association and Royal Pharmaceutical Society of Great Britain, London (link to current BNF)