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Lamotrigine

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  • Do not take more than the dose your doctor has prescribed for you.
  • Important: if you develop a skin rash, swollen glands or a high temperature, let your doctor know straight away.
  • Do not stop taking lamotrigine without speaking to your doctor first. Your doctor will need to reduce the dose you are taking gradually.

About lamotrigine

Type of medicine Antiepileptic
Used for The control of convulsions (fits or seizures)
Also called Lamictal
Available as Tablets
Dispersible tablets

Lamotrigine works by reducing the activity in the brain. It can be used on its own or alongside other medicines to control the convulsions (fits or seizures) in some forms of epilepsy. It is also helpful in preventing absence seizures (where people appear to 'switch off' for short periods of time).

Before taking lamotrigine

Before taking lamotrigine make sure your doctor or pharmacist knows:

  • If you are pregnant, trying for a baby, or breast-feeding.
  • If you suffer from liver or kidney problems.
  • If you have ever had an allergic reaction to this or any other medicine.
  • If you are taking any other medicines, including those available to buy without a prescription, herbal or complementary medicines.

How to take lamotrigine

  • Take lamotrigine exactly as directed by your doctor.
  • Always read the manufacturer's information leaflet, if possible before beginning treatment.
  • Lamotrigine tablets should be swallowed whole with a small glass of water.
  • Lamotrigine dispersible tablets may be chewed, dispersed in a little water, or swallowed whole with a small glass of water.
  • Do not stop taking lamotrigine without speaking to your doctor first. Your doctor will need to reduce the dose you are taking gradually.
  • Never take more than the prescribed dose. If you suspect that you or someone else has taken an overdose of lamotrigine contact your doctor or go to the accident and emergency department of your local hospital at once. Where possible take the container with you, even if it is empty.
  • Try to take your medicine at the same time each day to avoid missing any doses.
  • Lamotrigine is for you. Never give it to others, even if their condition appears to be the same as yours.

Getting the most from your treatment

  • Lamotrigine may cause your skin to become more sensitive to sunlight than it is usually. Avoid sunbeds and try to avoid the sun or use a sun cream higher than factor 15 until you know how your skin reacts.
  • While you are taking lamotrigine, there is a small risk that you may develop mood changes, distressing thoughts and feelings about suicide. If this happens, tell your doctor straight away.
  • Before taking any 'over-the-counter' medicines, check with your pharmacist which medicines are safe for you to take alongside lamotrigine.

Can lamotrigine cause problems

Along with their useful effects all medicines can cause unwanted side effects which usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side effects continue or become troublesome.

Common side-effects - these affect less than 1 in 10 people who take this medicine What can I do if I experience this
Feeling sick or being sick Eat little and often. Stick to simple foods such as dry toast and drink plenty of water to replace any lost fluids
Headache Ask your pharmacist to recommend a suitable pain killer. If the headache continues speak with your doctor
Drowsiness and blurred vision Make sure your reactions are normal before driving, operating machinery or doing any other jobs which could be dangerous if you were not fully alert or able to see properly

Other unwanted effects include: diarrhoea, tiredness, dizziness, difficulty sleeping, unsteadiness, tremor, irritability, mood changes, shakiness, confusion, joint pain, and problems with eyesight.

Important: let your doctor know straight away if you develop a high temperature, skin rash, swollen glands, unexplained bruising or flu-like infections.

How to store lamotrigine

  • Keep all medicines out of the reach of children.
  • Store in a cool, dry place, away from direct heat and light.
  • Never keep out of date or unwanted medicines. Take them to your local pharmacy which will dispose of unwanted medicines for you.

Important information about all medicines


  • Keep all medicines out of the sight and reach of children.
  • Make sure that the person prescribing this medicine knows about any other medicines that you are taking. This includes medicines you buy and herbal and homeopathic medicines.
  • If you buy any medicines check with a pharmacist that they are safe to take with your other medicines.
  • Before taking this medicine tell your doctor if you have ever had an allergic reaction after taking any medicine.
  • Never take more than the prescribed dose. If you suspect that you or someone else has taken an overdose of this medicine go to the accident and emergency department of your local hospital at once. Where possible take the container with you, even if it is empty.
  • If you are having any treatment like an operation or dental treatment tell the person carrying out the treatment which medicines you are taking.
  • Always read the printed information leaflet that comes with your medicine.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep out of date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.

References

  • British National Formulary; 54th Edition (September 2007) British Medical Association and Royal Pharmaceutical Society of Great Britain, London
  • Summary of Product Characteristics - Lamictal®, GlaxoSmithKline UK, electronic Medicines Compendium. Text revised March 2007, accessed November 2007.
Comprehensive patient resources are available at www.patient.co.uk
© EMIS 2008 DocID:
3443
DocRef:
dils2576
Last Updated:
29 Nov 2007
Date of Next Review:
28 Nov 2009
Version:
23

The authors and editors of this article are employed to create accurate and up to date content reflecting reliable research evidence, guidance and best clinical practice. They are free from any commercial conflicts of interest. Find out more about updating.

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