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About inositol nicotinate

This belongs to the group of medicines known as peripheral vasodilators.

Inositol nicotinate is used to treat circulatory problems, such as peripheral vascular disease and Raynaud's syndrome. Such problems can cause numbness, pain and discomfort in the hands and feet, due to bad circulation. Inositol Nicotinate relieves these symptoms by increasing the blood flow to the affected areas by widening the blood vessels.

Inositol nicotinate is available in tablet form.

It is also sometimes known as: Hexopal; Hexopal Forte. You may notice the use of any of these names on the packaging of your medicine.

Before taking inositol nicotinate

Before taking inositol nicotinate make sure your doctor or pharmacist knows:

  • if you are pregnant, trying for a baby or breast-feeding
  • if you have recently had a heart attack or a stroke
  • if you suffer from poor circulation to the brain
  • if you suffer from unstable angina
  • if you have ever had an allergic reaction to this or any other medicine
  • if you are taking any other medicines, including those available to buy without a prescription, herbal or complementary medicines

How to take inositol nicotinate

  • Always read the manufacturer's information leaflet, if possible, before beginning treatment.
  • Take inositol nicotinate exactly as directed by your doctor.
  • Do not stop taking inositol nicotinate, without speaking to your doctor first.
  • Try to take inositol nicotinate at the same times each day to avoid missing any doses.
  • If you miss a dose of inositol nicotinate take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue taking it at the usual times. Never take two doses at the same time to make up. If in doubt speak with your doctor or pharmacist.
  • Take inositol nicotinate with or immediately after food.
  • Inositol nicotinate is for you. Never give it to others even if their condition appears to be the same as yours.
  • Never take more than the prescribed dose. If you suspect that you or someone else has taken an overdose of inositol nicotinate contact your doctor or go to the accident and emergency department of your local hospital at once. Always take the container with you, if possible, even if it is empty.

Getting the most from your treatment

  • Before taking any 'over-the-counter' medicines, check with your pharmacist which medicines are safe for you to take alongside inositol nicotinate.
  • It may take some time for this medicine to work. If you feel that it is not working, do not stop taking it, instead consult your doctor.
  • Inositol nicotinate can cause dizziness. Make sure you know how you react to this medicine before driving, operating machinery or doing any other jobs which could be dangerous if you were to become dizzy.
  • Do not smoke. Smoking can narrow your blood vessels further and will aggravate your condition.
  • Keep your home warm. The cold cuts down the blood supply to the skin even before you feel cold. If you do go out in the cold, wrap up well in warm clothing, especially gloves and socks.
  • Regular exercise will help to improve your circulation. Your doctor can advise you on how much exercise and the type of exercise suitable for you.
  • Take good care of your hands and feet. Examine your hands, legs and feet regularly for any signs of damage or infection. If you notice any changes consult your doctor.
  • Before having any kind of surgery, including dental or emergency treatment, tell the doctor, dentist or surgeon you are taking inositol nicotinate.
  • Keep your regular appointments with your doctor so your progress can be checked.

Can inositol nicotinate cause problems?

As well as their useful effects all medicines can cause unwanted side effects. Speak to your doctor or pharmacist if any of the following side effects continue or become troublesome.

Flushing (redness of the face), dizziness, feeling or being sick, headache, being aware of your heartbeat, itching, pins and needles, rash, swollen ankles.

If you experience any other worrying or troublesome side effects, which you think may be due to this medicine, discuss them with your pharmacist.

How to store inositol nicotinate

  • Keep out of the reach of children.
  • Store in a cool, dry place, away from direct light and heat.
  • Never keep out of date or unwanted medicines. Discard them safely out of the reach of children or take them to your local pharmacist who will dispose of unwanted medicines for you.

© EMIS and Cegedim Pharmacy Services Ltd 2005   Updated: 20/10/2005   

Comprehensive patient resources are available at www.patient.co.uk


The authors and editors of this article are employed to create accurate and up to date content reflecting reliable research evidence, guidance and best clinical practice. They are free from any commercial conflicts of interest. Find out more about updating.

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