|Type of medicine||5HT3 antagonist anti-emetic|
|Used for||Prevention or treatment of sickness after chemotherapy, radiotherapy or surgery|
|Available as||Tablets and injection|
Chemotherapy, radiotherapy and surgery may all cause the release of a chemical called serotonin (5HT) in the digestive system and the brain. This serotonin acts on receptors called 5HT3 receptors which cause sickness and feelings of sickness. Granisetron works by blocking these 5HT3 receptors and therefore stops you from feeling or being sick.
Before taking granisetron
Before taking granisetron make sure your doctor or pharmacist knows:
- If you are pregnant, trying for a baby or breast-feeding.
- If you have heart problems such as an irregular heart beat.
- If you think you may have a blocked bowel.
- If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
- If you have ever had an allergic reaction to this or to any other medicine.
How to take granisetron
- Before taking granisetron, read the manufacturer's printed information leaflet.
- Take these tablets exactly as your doctor has told you to.
- Usually granisetron is taken within an hour of your chemotherapy or radiotherapy treatment beginning. Your doctor may ask you to take a further dose 12 hours later. If you are unsure about when to take your doses, check with your doctor.
- If you forget to take your dose, and you feel sick, take it as soon as you remember.
Can granisetron cause problems?
Along with their useful effects, all medicines can cause unwanted side-effects although not everyone experiences them. These usually improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.
|Common side-effects - these affect less than 1 in 10 people who take this medicine||What can I do if I experience this|
|Constipation||Try to eat a well balanced diet containing plenty of fibre, and drink 6 - 8 glasses of water each day|
|Headache||Ask your pharmacist to recommend a suitable painkiller. If the headache continues, speak with your doctor|
|Other side-effects include: diarrhoea, abdominal pain, sickness, weakness, high temperature, skin rash, and unusual body movements||If these become troublesome, speak with your doctor|
If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.
How to store granisetron
- Keep all medicines out of the reach and sight of children.
- Store in a cool, dry place, away from direct heat and light.
Important information about all medicines
Further reading & references
- British National Formulary; 60th Edition (September 2010) British Medical Association and Royal Pharmaceutical Society of Great Britain, London.
- Manufacturer's PIL, Kytril® Tablets 1 mg and 2 mg; Manufacturer's PIL, Kytril® Tablets 1 mg and 2 mg, Roche Products Limited, electronic Medicines Compendium. Dated January 2010.
|Original Author: Helen Allen||Current Version: Helen Allen|
|Last Checked: 18/11/2010||Document ID: 3602 Version: 22||© EMIS|
Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. EMIS has used all reasonable care in compiling the information but make no warranty as to its accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. For details see our conditions.