Glyceryl trinitrate (rectal)

About glyceryl trinitrate (rectal)

An anal fissure is a small tear of the skin of the anus. Glyceryl trinitrate ointment works by relaxing the muscle around the anus (the anal sphincter) which allows a good blood flow and enables the fissure to heal as quickly as possible. It may also ease the pain very quickly

Before using glyceryl trinitrate rectally

Before using glyceryl trinitrate rectally make sure your doctor or pharmacist knows:

• If you are pregnant, trying for a baby or breast-feeding.
• If you suffer from a heart condition, liver or kidney problems.
• If you suffer from hypotension (low blood pressure).
• If you have recently suffered a head injury or brain haemorrhage.
• If you have recently suffered a heart attack.
• If you suffer from anaemia (low levels of iron in the blood) or hypoxaemia (low levels of oxygen in the blood).
• If you suffer from thyroid problems.
• If you suffer from glaucoma (increased pressure in the eye).
• If you are taking any products to help treat erectile dysfunction (such as Viagra®).
• If you suffer from hypothermia (low body temperature).
• If you suffer from poor nutrition.
• If you are under 18 years of age.
• If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
• If you have ever had an allergic reaction to this or any other medicine.

How to use glyceryl trinitrate rectally

• Before beginning treatment, read the manufacturer's printed information leaflet.
• Use your ointment exactly as directed by your doctor.
• Squeeze 2.5 cm of ointment out of the tube onto your finger (a measuring line comes with the product to measure 2.5 cm of ointment), then place the ointment just inside the anus. A finger covering, such as cling film or a disposable glove, may be used to apply the ointment. Use the ointment every 12 hours until the pain goes away, or for up to a maximum of 8 weeks. Sometimes your doctor may advise you to apply the ointment around the rim of the anus rather than inside, to reduce headache that can occur as a side-effect of glyceryl trinitrate.

Getting the most from your treatment

• Try to avoid becoming constipated by eating a high-fibre diet and drinking 6-8 glasses of water a day.
• It is best not to drink alcohol while you are using glyceryl trinitrate. Alcohol can make any dizziness you feel worse. If you do drink alcohol, drink only a little and be aware of its effect on you.
• If you buy any medicines, check with a pharmacist that they are safe to take with your other medicines.
• If you miss using a dose of ointment, don't worry, just apply the next dose at the usual time. Do not use two doses at the same time to make up.

Can glyceryl trinitrate rectally cause problems?

Along with their useful effects all medicines can cause unwanted side effects, which usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side effects continue or become troublesome.

If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.

How to store glyceryl trinitrate (rectal)

• Do not store or use the ointment for longer than 8 weeks once it has been opened.
• Keep all medicines out of the reach of children.
• Store in a cool, dry place, away from direct heat and light.

Important information about all medicines