Gentamicin with hydrocortisone ear drops


  • Gentamicin with hydrocortisone is used to treat inflammatory conditions of the ear, particularly those caused by a bacterial infection or eczema.
  • Follow the instructions you have been given carefully.
  • These ear drops must not be used if the bottle has been opened for longer than four weeks.
Type of medicine Anti-infective and anti-inflammatory ear drops
Used for Reducing inflammation and treating infections in the ear
Also called Gentisone HC®
Available as Ear drops

Gentamicin with hydrocortisone is used to treat inflammatory conditions of the ear, particularly those caused by a bacterial infection or eczema. It can also be used to prevent or treat infections in the ear following an injury or surgery.

Gentamicin is used to treat bacterial infections by killing the bacteria responsible for causing the infection. Hydrocortisone is used to relieve inflammation, itching and pain.

Before using gentamicin with hydrocortisone ear drops make sure your doctor or pharmacist knows:

  • If you are pregnant, trying for a baby or breast-feeding.
  • If you have a perforated (burst) ear drum.
  • If you have ever had an allergic reaction to gentamicin, any other medicine or preservative (for example, benzalkonium chloride).
  • Before starting this treatment, read the manufacturer's printed information leaflet.
  • Follow the instructions you have been given carefully. You will be told how often to use the drops and for how long.
  • Try not to miss doses. If you do miss a dose, then apply the missed dose as soon as you remember.

How to use gentamicin with hydrocortisone ear drops:

  • Wash your hands well before use.
  • Clean your ear with warm water and pat it dry.
  • Remove the cap.
  • Lie down or tilt your head a little so that the affected ear is facing upwards.
  • Gently pull your earlobe to straighten the ear canal.
  • Hold the container upside down near to the ear. Try not to touch the inside of your ear as you do this.
  • Apply enough pressure to the container to release two to three drops.
  • Keep your ear facing upwards for a few minutes to allow the solution to come into contact with the affected area.
  • Repeat the process in your other ear if you have been asked to use the drops in both ears.
  • Replace the cap.
  • Wash your hands.
  • These ear drops are only intended for short-term use.
  • If your symptoms do not improve within a few days or if they become worse, speak with your doctor.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. These usually improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.

Possible side-effects What can I do if I experience this
Mild irritation, burning or stinging sensation You may experience this when you first start using these drops. If it continues or is severe, speak with your doctor

If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.

  • Keep all medicines out of the reach and sight of children.
  • Store in a cool, dry place, away from direct heat and light.
  • If there is any preparation left in the container after you have finished your course of treatment, do not keep it. These ear drops must not be used if the bottle has been opened for longer than four weeks.

  • If you suspect that someone has swallowed some of this medicine, go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • If you buy any medicines, check with a pharmacist that they are safe to take/use with your other medicines.
  • Never keep out of date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.

Further reading & references

  • British National Formulary; 60th Edition (September 2010) British Medical Association and Royal Pharmaceutical Society of Great Britain, London.
Original Author: Helen Allen Current Version:
Last Checked: 26/01/2011 Document ID: 3666  Version: 22 © EMIS

Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. EMIS has used all reasonable care in compiling the information but make no warranty as to its accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. For details see our conditions.

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