About fluphenazine depot injection
|Type of medicine||Antipsychotic|
|Used for||Maintenance of symptoms in schizophrenia and other mental health problems affecting thoughts, feelings and behaviours|
|Also called||Modecate®, Modecate Concentrate®|
Fluphenazine is used to treat mental health problems like schizophrenia, which affect the way you think, feel or behave. These problems are thought to be caused by over-activity of certain areas of the brain. Fluphenazine works by blocking receptors in your brain to alter the activity in these areas, which helps to improve disturbed thoughts and behaviours.
Fluphenazine depot injection is used for the maintenance of your symptoms. It is a long acting medicine that is injected into the muscles of your buttock or thigh. It lasts for between two and four weeks, so you do not need to remember to take tablets each day.
Before using fluphenazine depot injection
Before using fluphenazine depot injection make sure your doctor or pharmacist knows:
- If you are pregnant, trying for a baby or breast-feeding.
- If you suffer from a heart condition or blood vessel disease.
- If you suffer from cerebral atherosclerosis (thickening or hardening of the arteries in the brain).
- If you have liver or kidney problems.
- If you have breathing problems.
- If you suffer from depression.
- If you suffer from Parkinson's disease.
- If you have a condition called phaeochromocytoma (a tumour on your adrenal gland).
- If you have epilepsy, myasthenia gravis (a muscle weakening disease), prostate problems or glaucoma.
- If you have ever had jaundice (yellowing of the skin and whites of the eyes) or any problems with your blood.
- If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
- If you have ever had an allergic reaction to this or any other medicine.
How to use fluphenazine depot injection
- Before beginning treatment, read the manufacturer's printed information leaflet.
- Fluphenazine will be given to you by your doctor or nurse.
- If you haven't received an injection like fluphenazine before, a small dose is usually given one week before your normal dose to test how well you tolerate the medicine.
- It can take a few weeks before you feel the full effect of fluphenazine. Your doctor will decide how long your treatment with fluphenazine will last.
- Your treatment will require careful monitoring to make sure that you get the best possible effect from fluphenazine. Keep your regular doctor's appointment so your progress can be checked.
Getting the most from your treatment
- If you start or stop smoking whilst you are being treated with fluphenazine, make sure that you tell your doctor. The dose of your fluphenazine may need to be adjusted.
- Suicidal thoughts may be associated with medicines like fluphenazine. You may be at risk of such thoughts early in your treatment, if you have previously thought about harming yourself, or if you are a young adult. Tell your doctor straight away if you are having any thoughts of harming yourself.
- Fluphenazine may cause your skin to become more sensitive to sunlight. Use a sunscreen that protects against UVA light and has a sun protection factor (SPF) of at least 15, especially in strong sunlight or until you know how your skin reacts. Do not use sunbeds.
- If you are having any dental treatment or an operation, tell the person carrying out the treatment which medicines you are taking.
- If you buy any medicines, check with a pharmacist that they are safe to take with fluphenazine.
Can fluphenazine depot injection cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. These usually improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.
|Possible side-effects||What can I do if I experience this|
|Pain at injection site||This should pass quickly|
|Drowsiness, dizziness, blurred vision||Make sure your reactions are normal before driving, operating machinery or doing any other jobs which could be dangerous if you were not fully alert. Do not drink alcohol while you are being treated with fluphenazine as it will increase drowsiness|
|Headache||Ask your pharmacist to recommend a suitable painkiller. If the headache continues, speak with your doctor|
|Constipation||Drink plenty of water and eat plenty of fruit and vegetables|
|Dry mouth||Try chewing sugar-free gum or sucking sugar-free sweets|
|Difficulty passing urine, slow movements, difficulty sleeping, changes in mood||Discuss these with your doctor if any become troublesome|
Important: If you experience 'flu-like' symptoms including stiffness, with a high temperature, confusion, abnormal paleness, a racing heartbeat, and sweating, contact your doctor immediately or go to your local accident and emergency department without delay.
Important: If you experience abnormal face or body movements, restlessness, or involuntary movements, discuss these with your doctor.
If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.
How to store fluphenazine depot injection
- Keep all medicines out of the reach and sight of children.
- Store in a cool, dry place, away from direct heat and light.
Important information about all medicines
Further reading & references
- British National Formulary; 60th Edition (September 2010) British Medical Association and Royal Pharmaceutical Society of Great Britain, London.
- Manufacturer's PIL, Modecate Injection®; Manufacturer's PIL, Modecate Injection®, sanofi-aventis, electronic Medicines Compendium. Dated January 2010.
|Original Author: Helen Allen||Current Version: Pippa Crossley|
|Last Checked: 20/04/2011||Document ID: 3682 Version: 23||© EMIS|
Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. EMIS has used all reasonable care in compiling the information but make no warranty as to its accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. For details see our conditions.