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Fluoxetine

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  • Important: Tell your doctor straight away if you are having thoughts of harming yourself or ending your life.
  • Do not stop taking these tablets without speaking to your doctor first. Stopping suddenly can cause problems.
  • Fluoxetine may slow your reactions. Make sure your reactions are normal before driving.

About fluoxetine

Type of medicine Selective serotonin re-uptake inhibitor (SSRI) antidepressant
Used for Depression
Bulimia nervosa
Obsessive-compulsive disorder
Also called Oxactin®, Ranflutin®, Prozep®, Prozac®, Prozit®
Available as Capsules and oral liquid

Certain chemicals in our brain control how we feel. It is thought that low levels of a chemical called serotonin can lead to depression and other conditions. Fluoxetine works by helping to regulate serotonin levels in our body, easing the symptoms of depression, the eating disorder bulimia nervosa, and obsessive-compulsive disorder.

Before taking fluoxetine

Before taking fluoxetine make sure your doctor or pharmacist knows:

  • If you are pregnant, trying for a baby or breast-feeding.
  • If you suffer from heart, liver or kidney problems.
  • If you are under 18 years of age.
  • If you suffer from epilepsy, diabetes mellitus, glaucoma (increased eye pressure), or a bleeding disorder.
  • If you have ever suffered from mania (great excitement, hallucinations, difficulty in concentrating or staying still).
  • If you are being treated with ECT (electroconvulsive therapy).
  • If you have ever had an allergic reaction to this or any other medicine.
  • If you have taken a monoamine oxidase inhibitor (MAOI) antidepressant within the last two weeks.
  • If you are taking any other medicines, including those available to buy without a prescription, herbal or complementary medicines.

How to take fluoxetine

  • Before beginning treatment, read the manufacturer's printed information leaflet.
  • Take fluoxetine exactly as you have been directed by your doctor.
  • Try to avoid missing any doses. If you do forget to take a dose, take one as soon as you remember unless it is nearly time for your next dose. Do not take two doses on the same day to make up.
  • You may have to take fluoxetine for several weeks before you feel the full effect.
  • Do not stop taking fluoxetine without speaking to your doctor first. Your doctor will want to reduce your dose gradually as stopping suddenly can cause problems.

Getting the most from your treatment

  • Fluoxetine may slow your reactions. Make sure your reactions are normal before driving or doing any other tasks that would be dangerous if you were not fully alert.
  • Avoid drinking alcohol whilst you are taking fluoxetine.
  • Fluoxetine may cause your skin to become more sensitive to sunlight than it usually is. Avoid sunbeds and try to avoid sunlight or use a suncream higher than factor 15 until you know how your skin reacts.
  • If you are having any treatment like an operation or dental treatment, tell the person carrying out the treatment that you are taking fluoxetine.
  • Keep your regular doctor's appointment so your progress can be monitored.
  • If you buy any medicines, check with a pharmacist that they are safe to take with fluoxetine.

Can fluoxetine cause problems?

Along with their useful effects all medicines can cause unwanted side effects, which usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side effects continue or become troublesome.

Common side-effects - these affect less than 1 in 10 people who take this medicine What can I do if I experience this
Feeling or being sick, diarrhoea Eat little and often. Try simple foods such as dry toast and drink plenty of water to replace any lost fluids
Constipation Try to eat a well-balanced diet containing plenty of fibre and drink 6-8 glasses of water each day
Dry mouth Try chewing sugar-free gum, pieces of ice or sugar-free sweets
Headache Ask your pharmacist to recommend a suitable pain-killer. If the headache continues, speak with your doctor
Sleepiness, dizziness (especially when standing or sitting up), weakness Make sure your reactions are normal before driving, operating machinery or doing any other jobs which could be dangerous if you were not fully alert
Indigestion, abdominal pain, flushing, difficulty breathing, sore throat, chills, changes in taste, yawning, confusion, poor concentration, hair loss, reduced appetite, weight loss, joint or muscle pain, nervousness, anxiety, difficulty sleeping, shakiness, sexual difficulties, difficulty or frequency urinating (passing water), sweating, mood changes, and unusual movements Speak with your doctor if any of these become troublesome

Important: If you develop a rash, itching, swelling of the mouth or face, or have difficulty swallowing or breathing, then contact your doctor straight away or go to the accident and emergency department of your local hospital.

Important: If you have any thoughts of harming yourself or ending your life whilst you are taking fluoxetine, tell your doctor straight away.

If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.

How to store fluoxetine

  • Keep all medicines out of the reach of children.
  • Store in a cool, dry place, away from direct heat and light.

Important information about all medicines


  • Never take more than the prescribed dose. If you suspect that you or someone else has taken an overdose of this medicine, go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep out of date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.

References

Comprehensive patient resources are available at www.patient.co.uk
© EMIS 2008 DocID:
3418
DocRef:
dils2501
Last Updated:
14 Sep 2008
Date of Next Review:
14 Sep 2010
Version:
22

The authors and editors of this article are employed to create accurate and up to date content reflecting reliable research evidence, guidance and best clinical practice. They are free from any commercial conflicts of interest. Find out more about updating.

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