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Ergotamine

  • Ergotamine will only treat a migraine headache that has already begun. It will not prevent the migraine headaches or reduce the number of attacks.
  • If you have already taken a course of ergotamine then do not take another in the next 4 days, and do not take more than 2 courses of ergotamine a month.
  • These tablets should not be taken on a regular basis.
  • Ergotamine is not recommended for children under 12 years of age.

About ergotamine

Type of medicineErgot alkaloid
Used forTreatment of migraine headaches
Also calledCafergot® (ergotamine tartrate with caffeine)
Available asTablets and suppositories

Ergotamine is used to treat migraines which have not responded to simple painkillers. Ergotamine tablets and suppositories are used at the first sign of a migraine attack to relieve the symptoms and to stop the attack getting worse.

Migraine can be caused by the widening of blood vessels in the head. Ergotamine eases the pain associated with migraine by narrowing these blood vessels.

Preparations containing ergotamine also contain caffeine which is used to enhance the analgesic (pain-killing) effects.

Ergotamine may also be used in combination with an anti-sickness medicine called cyclizine. There is more information about this in a separate leaflet called "Ergotamine, cyclizine and caffeine."

Before taking ergotamine

Before taking ergotamine make sure your doctor or pharmacist knows:

  • If you are pregnant, trying for a baby or breast-feeding.
  • If you suffer from kidney, liver or thyroid problems.
  • If you suffer from Raynaud's syndrome.
  • If you suffer from heart or blood circulation problems.
  • If you suffer from hypertension (high blood pressure) or porphyria (a rare blood disorder).
  • If you smoke.
  • If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
  • If you have ever had an allergic reaction to this or to any other medicine.

How to take ergotamine

  • Before beginning treatment, read the manufacturer's printed information leaflet.
  • Take your medication exactly as directed by your doctor. Never take more than your prescribed dose of ergotamine.

If you have been given ergotamine tablets:

  • As soon as you feel you are getting a migraine, take 1 or 2 tablets as directed by your doctor.
  • Do not take more than 4 tablets in 24 hours and leave at least 4 days before taking any more tablets, if required.
  • Never take more than 8 tablets in one week.

If you have been given ergotamine suppositories:

  • Wash your hands before and after using the suppositories.
  • As soon as you feel you are getting a migraine, insert 1 suppository into the back passage (rectum) as directed by your doctor. If this provides no relief, 1 further suppository may be inserted into the rectum.
  • Do not use more than 2 suppositories in 24 hours and leave at least 4 days before using any more suppositories, if required.
  • Never use more than 4 suppositories in one week.

Getting the most from your treatment

  • If you are having any treatment like an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking.
  • Keep your regular doctor's appointment so your progress can be monitored.
  • Ergotamine must not be taken on a daily basis to prevent migraine.
  • If you buy any medicines, check with a pharmacist that they are safe to take with your other medicines.

Can ergotamine cause problems?

Along with their useful effects, all medicines can cause unwanted side-effects although not everyone experiences them. Speak with your doctor or pharmacist if any of the following side effects continue or become troublesome.

Common side-effects - these affect less than 1 in 10 people who take this medicineWhat can I do if I experience this
DizzinessMake sure your reactions are normal before driving, operating machinery or doing any other jobs which could be dangerous if you were not fully alert
Stomach pain, feeling or being sickEat little and often. Stick to simple foods

Important: if you experience numbness or tingling in your hands or feet, pain in your chest or are passing less urine than normal then speak with your doctor immediately or go to your local accident and emergency department without delay.

If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.

How to store ergotamine

  • Keep all medicines out of the reach and sight of children.
  • Store in a cool, dry place, away from direct heat and light.

Important information about all medicines


  • Never take more than the prescribed dose. If you suspect that you or someone else has taken an overdose of this medicine, go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.

References

Comprehensive patient resources are available at www.patient.co.uk
© EMIS 2010DocID: 3245DocRef: dils2124Last Reviewed: 8 Nov 2010Version: 22
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