Eplerenone

  • Eplerenone tablets are taken once a day.
  • Do not use salt substitutes while you are taking eplerenone.
  • Make sure your doctor knows about all other medicines you are taking alongside eplerenone.

About eplerenone

Type of medicineAldosterone antagonist
Used forHeart failure
Also calledInspra®
Available asTablets

Eplerenone is used alongside other medicines to help prevent any worsening of your heart failure. You may have been given it if the pumping action of your heart is still reduced despite your other treatment, or if you have recently had a heart attack.

Before taking eplerenone

Before taking eplerenone make sure your doctor or pharmacist knows:

  • If you have kidney or liver problems.
  • If you have been told you have high levels of potassium in your blood.
  • If you are pregnant, trying for a baby or breast-feeding.
  • If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
  • If you have ever had an allergic reaction to this or any other medicine.

How to take eplerenone

  • Before starting this treatment, read the manufacturer's printed information leaflet.
  • Take eplerenone exactly as your doctor has told you. It is taken once daily.
  • Swallow the tablets whole with a drink of water. It is not important whether you take your dose before or after food.
  • Try to take eplerenone at the same time each day to avoid missing any doses.
  • If you forget to take a dose, take one as soon as you remember if this is during the same day as your dose was due. If you do not remember until the next day, skip the forgotten dose and just take the dose that is due. Do not take two doses at the same time to make up for a missed dose.

Getting the most from your treatment

  • Do not use salt substitutes or take potassium supplements with eplerenone.
  • Keep your regular appointments with your doctor so your progress can be monitored.
  • If you buy any medicines, check with a pharmacist that they are safe to take with eplerenone and your other medicines.

Can eplerenone cause problems?

Along with their useful effects, all medicines can cause unwanted side-effects although not everyone experiences them. These usually improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.

Common side-effects - these affect less than 1 in 10 people who take this medicineWhat can I do if I experience this
Dizziness, light-headednessGetting up more slowly may help. If you begin to feel dizzy, lie down so that you do not faint, then sit for a few moments before standing. Do not drive or operate machinery if you are feeling dizzy
Feeling sickEat little and often. Stick to simple foods
DiarrhoeaDrink plenty of water to replace lost fluids
Other common side-effects: skin rash, kidney problemsLet your doctor know if you develop a rash or if you have any problems passing urine

If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.

How to store eplerenone

  • Keep all medicines out of the reach and sight of children.
  • Store in a cool, dry place, away from direct heat and light.

Important information about all medicines

  • If you are having any treatment like an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking.
  • Never take more than the prescribed dose. If you suspect that you or someone else has taken an overdose of this medicine, go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep out of date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.

References

The pharmacists and clinicians responsible for the production of this document are:
Original Author: Helen Allen
Last Checked: 13 Jan 2011
Current Version: Helen Allen
Document ID: 13597  Version: 2
Peer Reviewer: Prof Cathy Jackson
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