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Eletriptan


  • Take one dose at the start of a migraine attack. If your migraine is not eased after this first dose, do not take a second dose for the same attack. If your migraine goes away but then returns, you may take a second dose at least two hours after the initial dose. Do not take more than two doses in 24 hours.
  • Eletriptan can cause drowsiness. Make sure you know how you react to this medicine before driving, operating machinery or doing any other jobs which could be dangerous if you were not fully alert.
  • You may experience sensations of pressure or tightness in any part of the body, including the throat and chest. If these sensations continue or become intense, stop taking eletriptan and contact your doctor as soon as possible.

About eletriptan

Type of medicine5HT1-receptor Agonist
Used forTreatment of acute migraine attacks
Also calledRelpax®
Available asTablets

It is not clear what causes migraine. It is thought that some chemicals in the brain increase in activity, and as a result parts of the brain then send out confused signals which result in the symptoms of migraine.

It is also not clear why people with migraine should develop these chemical changes and most migraine attacks occur for no apparent reason. In some people however, there may be things which trigger an attack, like certain foods or drinks.

Eletriptan works by stimulating receptors called serotonin (or 5HT) receptors that are found in the brain. This improves the symptoms felt during a migraine.

Before taking eletriptan

Before taking eletriptan make sure your doctor or pharmacist knows:

  • If you are pregnant, trying for a baby or breast-feeding.
  • If you are aged over 65 years or under 18 years old.
  • If you have any heart problems, including heart failure or an irregular heartbeat.
  • If you have Prinzmetal's angina or circulatory problems such as Raynaud's disease.
  • If you have recently suffered a heart attack, stroke or TIA (sometimes known as a mini-stroke).
  • If you have high blood pressure.
  • If you have liver or kidney problems.
  • If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
  • If you have ever had an allergic reaction to this or any other medicine.

How to take eletriptan

  • Before beginning treatment, read the manufacturer's printed information leaflet.
  • Take eletriptan exactly as directed by your doctor.
  • The usual dose is one 40 mg tablet taken at the start of your migraine attack, repeated after two hours if your migraine returns. If your migraine is not eased by the first dose, do not take a second dose for the same attack.
  • If one 40 mg tablet is inadequate, the dose can be increased to two tablets (80 mg) for future attacks. Do not take more than 80 mg of eletriptan in 24 hours.

Getting the most from your treatment

  • Do not take other migraine treatments as well as eletriptan. If you have been taking another 5HT1 agonist (almotriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan or zolmitriptan), including any bought from a pharmacy, you should wait at least 24 hours before taking eletriptan.
  • If you find that eletriptan does not relieve your migraine, make an appointment to discuss this with your doctor.
  • If you are having an operation or any dental treatment, tell the person carrying out the treatment which medicines you are taking.
  • If you buy any medicines, check with a pharmacist that they are safe to take with your other medicines.

Can eletriptan cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. These usually improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.

Possible side-effectsWhat can I do if I experience this
Dizziness and drowsiness, flushing, feeling of weaknessMake sure your reactions are normal before driving, operating machinery or doing any other jobs which could be dangerous if you were not fully alert.
Feeling of tingling, heat, heaviness, pressure or tightness in any part of the body, including the throat or chestIf these continue or become intense, stop taking eletriptan and contact your doctor as soon as possible
Feeling or being sick, stomach pains and indigestionEat little and often. Stick to simple foods. Speak to your doctor if any of these become troublesome
Dry mouthTry chewing sugar-free gum or sugar-free sweets
Increased heart rate or sensation of a fluttering heartContact your doctor if these side-effects continue

If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.

How to store eletriptan

  • Keep all medicines out of the reach and sight of children.
  • Store in a cool, dry place, away from direct heat and light.

Important information about all medicines


  • Never take more than the prescribed dose. If you suspect that you or someone else has taken an overdose of this medicine, go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep out of date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.

References

Comprehensive patient resources are available at www.patient.co.uk


© EMIS 2011 - Author: - Reviewer: Dr Cathy Jackson - Document ID: 3828 - Version: 23 - Reviewed: 9 May 2011

For the planned review period see the Data Creation and Quality Control Process.
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