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Domperidone
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About domperidone
| Type of medicine | Dopamine antagonist |
| Used for | The relief of sickness, feeling sick, or the regurgitation of stomach contents The discomfort of indigestion with a feeling of bloatedness |
| Also called | Motilium® |
| Available as | Tablets, oral suspension and suppositories |
Domperidone works by helping to move food faster through your digestive system. This helps prevent feelings of sickness, bloatedness and regurgitation.
Before taking or using domperidone
Before taking or using domperidone make sure your doctor or pharmacist knows:
- If you are pregnant, trying for a baby or breast-feeding.
- If you have kidney or liver problems.
- If you have prolactinoma (a tumour of the pituitary gland).
- If you have a bowel blockage or tear, or any bleeding from your bowel.
- If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
- If you have ever had an allergic reaction to this or any other medicine.
How to take or use domperidone
- Before beginning treatment, read the manufacturer's printed information leaflet.
- Take domperidone exactly as directed by your doctor. If you are taking the tablets or oral suspension, swallow your dose with a drink of water, half an hour before a meal and at bedtime if needed. If you are using the suppositories, follow the information in the leaflet provided.
- Domperidone is not generally recommended for children except to control sickness following cancer treatment.
Getting the most from your treatment
- If you buy any medicines, check with a pharmacist that they are safe to take with domperidone.
- If you are having any treatment like an operation or dental treatment, tell the person carrying out the treatment that you are taking domperidone.
Can domperidone cause problems?
Along with their useful effects all medicines can cause unwanted side-effects. These usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.
| Rare side-effects - these affect less than 1 in 1,000 people who take this medicine | What can I do if I experience this |
| Drowsiness | Make sure your reactions are normal before driving, operating machinery or doing any other jobs which would be dangerous if you were not fully alert |
| Enlarged breasts, unusual production of breast milk, reduced interest in sex, and irregular menstrual periods | Let your doctor know |
If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.
How to store domperidone
- Keep all medicines out of the reach and sight of children.
- Store in a cool, dry place, away from direct heat and light.
Important information about all medicines
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References
- Manufacturer's PIL, Motilium® 10 mg Tablets, Winthrop Pharmaceuticals UK Ltd, electronic Medicines Compendium. Dated January 2008, accessed August 2009.
- Manufacturer's PIL, Domperidone 1 mg/ml Suspension, Winthrop Pharmaceuticals UK Ltd, electronic Medicines Compendium. Dated September 2008, accessed August 2009.
- British National Formulary; 57th Edition (March 2009) British Medical Association and Royal Pharmaceutical Society of Great Britain, London.
The authors and editors of this article are employed to create accurate and up to date content reflecting reliable research evidence, guidance and best clinical practice. They are free from any commercial conflicts of interest. Find out more about updating.
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