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Cycloserine

  • Cycloserine is used alongside other medicines to treat tuberculosis (TB).
  • You will probably need to have regular blood tests while you are taking this medicine.
  • Do not stop taking cycloserine without speaking to your doctor first. You must complete the course.

About cycloserine

Type of medicineAntituberculosis drug
Used forTuberculosis
Available asCapsules

Cycloserine is used alongside other medicines to treat tuberculosis.

It is a type of antibiotic which works by acting on the cell walls of the bacteria responsible for the tuberculosis (TB). The cell walls do not form correctly causing them to break and the bacteria is killed.

Before taking cycloserine

Before taking cycloserine make sure your doctor or pharmacist knows:

  • If you are pregnant, trying for a baby or breast-feeding.
  • If you have liver or kidney problems.
  • If you drink excessive amounts of alcohol.
  • If you have porphyria (a rare blood disorder).
  • If you suffer from mental health problems such as psychosis, depression or severe anxiety.
  • If you have epilepsy or any other condition that causes convulsions (fits).
  • If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
  • If you have ever had an allergic reaction to this or any other medicine.

How to take cycloserine

  • Before beginning treatment, read the manufacturer's printed information leaflet.
  • Take cycloserine exactly as directed by your doctor.
  • Try to take cycloserine at the same times each day to avoid missing any doses.
  • If you forget to take a dose, take one as soon as you remember but do not take two doses at the same time to make up. If in doubt, speak to your pharmacist or doctor.
  • Do not stop taking cycloserine without speaking to your doctor first. You must complete the course of cycloserine.

Getting the most from your treatment

  • It is important to keep your appointments to check on your progress as you will probably need to have regular blood tests while you are taking this medicine.
  • Do not drink alcohol while you are taking cycloserine capsules because they can cause drowsiness and dizziness, and drinking alcohol will increase these feelings.
  • If you are having any treatment like an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking.
  • If you buy any medicines, check with a pharmacist that they are safe to take with your other medicines.

Can cycloserine cause problems?

Along with their useful effects all medicines can cause unwanted side-effects. These usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.

Common side-effects - these affect less than 1 in 10 people who take this medicineWhat can I do if I experience this
HeadacheAsk your pharmacist to recommend a suitable painkiller. Let your doctor know if the headache continues
Dizziness, vertigo (a spinning sensation), drowsinessMake sure your reactions are normal before driving, operating machinery, or doing any other things which would be dangerous if you were not fully alert
Shakiness, fits, confusion, changes in mood, skin rashes, and dermatitisLet your doctor know if you experience any of these

If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.

How to store cycloserine

  • Keep all medicines out of the reach and sight of children.
  • Store in a cool, dry place, away from direct heat and light.

Important information about all medicines


  • Never take more than the prescribed dose. If you suspect that you or someone else has taken an overdose of this medicine, go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.

References

  • British National Formulary; 58th Edition (September 2009) British Medical Association and Royal Pharmaceutical Society of Great Britain, London (link to current BNF).
Comprehensive patient resources are available at www.patient.co.uk
© EMIS 2010DocID: 3331DocRef: dils2300Last Reviewed: 15 Feb 2010Version: 22
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