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Cyclopenthiazide

  • Cyclopenthiazide belongs to the group of medicines known as thiazide diuretics.
  • Thiazide diuretics are often referred to as water tablets.
  • Cyclopenthiazide removes excess water from the body by increasing how often you pass water.
  • People with high blood pressure often do not feel unwell, but left untreated, high blood pressure can harm the heart and damage blood vessels.

About cyclopenthiazide

Type of medicineThiazide diuretic
Used forOedema
Hypertension
Heart failure
Also calledNavidrex®
Available asTablets

Cyclopenthiazide works on the kidney. It is used to treat hypertension (high blood pressure), oedema (fluid retention) and heart failure (a condition where the pumping action of the heart is reduced). It removes excess water from the body by increasing how much and how often you pass water. This removal of fluid reduces blood pressure and helps reduce the work of the heart.

Before taking cyclopenthiazide

Before taking cyclopenthiazide make sure your doctor or pharmacist knows:

  • If you are pregnant, trying for a baby or breast-feeding.
  • If you have liver or kidney problems.
  • If you have diabetes.
  • If you suffer from gout or hyperuricaemia (high blood uric acid).
  • If you have systemic lupus erythematosus (SLE).
  • If you have Addison's disease or another adrenal gland disorder.
  • If you have been told you have low levels of potassium or sodium in your blood, or high levels of calcium.
  • If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
  • If you have ever had an allergic reaction to this or any other medicine.

How to take cyclopenthiazide

  • Before beginning treatment, make sure you read the manufacturer's printed information leaflet.
  • Take cyclopenthiazide exactly as directed by your doctor.
  • Cyclopenthiazide will make you want to go to the toilet more often, so your doctor or pharmacist will usually advise you to take your dose in the morning.
  • If you miss a dose of cyclopenthiazide take it as soon as you remember. However, if it is after 6 pm in the afternoon, skip the missed dose and continue taking it at the usual times the next day. Do not take two doses together to make up for a missed dose.

Getting the most from your treatment

  • Diuretics like cyclopenthiazide help you to lose water. On occasions you may lose too much and become dehydrated leaving you feeling thirsty, your mouth dry, and your skin looking and feeling dry. Let your doctor know if this happens.
  • It is important to follow any dietary advice that you have been given by your doctor or nurse.
  • Many patients with high blood pressure do not feel unwell but, left untreated, high blood pressure can harm the heart and damage blood vessels, resulting in a heart attack, stroke, heart failure or kidney failure. Do not stop taking cyclopenthiazide without speaking to your doctor first.
  • If you have diabetes, cyclopenthiazide may affect your blood sugar levels. Test your urine or blood regularly. Speak to your doctor or pharmacist if you notice any changes.

Can cyclopenthiazide cause problems?

Along with their useful effects all medicines can cause unwanted side-effects. These usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.

Common side-effects - these affect less than 1 in 10 people who take this medicineWhat can I do if I experience this
Mild gastrointestinal effects (feeling sick, stomach pain)Eat little and often. Try taking your dose after food
Dizziness, particularly when getting upGetting up and moving more slowly should help

How to store cyclopenthiazide

  • Keep all medicines out of the reach and sight of children.
  • Store in a cool, dry place, away from direct heat and light.

Important information about all medicines


  • Keep all medicines out of the sight and reach of children.
  • Make sure that the person prescribing this medicine knows about any other medicines that you are taking. This includes medicines you buy and herbal and homeopathic medicines.
  • If you buy any medicines check with a pharmacist that they are safe to take with your other medicines.
  • Before taking this medicine tell your doctor if you have ever had an allergic reaction after taking any medicine.
  • Never take more than the prescribed dose. If you suspect that you or someone else has taken an overdose of this medicine go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
  • If you are having any treatment like an operation or dental treatment tell the person carrying out the treatment which medicines you are taking.
  • Always read the printed information leaflet that comes with your medicine.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.

References

  • British National Formulary; 58th Edition (September 2009) British Medical Association and Royal Pharmaceutical Society of Great Britain, London (link to current BNF).
Comprehensive patient resources are available at www.patient.co.uk
© EMIS 2010DocID: 617DocRef: dils2899Last Reviewed: 12 Jan 2010Version: 23
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