Clindamycin


  • Spread your doses out evenly throughout the day. Clindamycin is usually taken every six hours.
  • Swallow clindamycin capsules with a full glass of water.
  • If you develop diarrhoea while you are taking clindamycin, contact your doctor straight away for advice before taking any more doses.
Type of medicine Antibiotic
Used for Infections
Also called Dalacin® C
Available as Capsules and injection

Clindamycin is used to treat serious bacterial infections, particularly those in bones or joints. It is also used to treat tooth infections where other antibiotics have not worked. It works by killing the bacteria which cause the infection.

Clindamycin is also available as a skin preparation for the treatment of acne, and as a cream for use in vaginal infections. There are two separate leaflets available for these called Clindamycin (topical) and Clindamycin (vaginal) respectively.

Before taking clindamycin make sure your doctor or pharmacist knows:

  • If you are pregnant or breast-feeding.
  • If you have any bowel problems which regularly cause diarrhoea.
  • If you have porphyria (a rare blood disorder).
  • If you are taking other medicines, including those available to buy without a prescription, herbal and complementary medicines.
  • If you have ever had an allergic reaction to this or any other medicine.
  • Before starting this treatment, read the manufacturer's printed information leaflet from inside the pack.
  • Take clindamycin exactly as your doctor has told you.
  • Swallow clindamycin capsules whole (not crushed or chewed), with a full glass of water.
  • Spread your doses out evenly throughout the day. Clindamycin is usually taken every six hours.
  • It is not important whether you take clindamycin before, during or after food.
  • Keep taking this antibiotic until the course is finished unless you are told to stop. This is important in order to prevent the infection from coming back.
  • If you forget to take a dose, take it as soon as you remember unless it is nearly time for your next dose, in which case leave out the missed dose. Do not take two doses together to make up for a forgotten dose.
  • Keep your regular appointments with your doctor so your progress can be monitored. If you are taking clindamycin for longer than 10 days, you may need to have blood tests to check on your liver and kidneys.
  • If you are using oral combined hormonal contraception (the 'pill'), additional contraceptive precautions such as condoms are not required during a course of this antibiotic unless you are sick or have diarrhoea. If you need further advice, speak with your doctor or pharmacist.
  • This antibiotic may stop the oral typhoid vaccine from working. If you are having any vaccinations, make sure the person treating you knows that you are taking this medicine.
  • If you still feel unwell after completing your course of this antibiotic, make another appointment to see your doctor.
  • Some people develop thrush (redness and itching in the mouth or vagina) after taking a course of antibiotics. If you think you have thrush, speak with your doctor or pharmacist for advice.
  • If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking clindamycin.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. These usually improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.

Possible side-effects What can I do if I experience this
Diarrhoea Important: You must let your doctor know about this straight away
Feeling or being sick, abdominal discomfort Stick to simple or bland foods
Skin rashes or itching If this becomes troublesome or severe, let your doctor know
Sore throat, throat ulcers, and changes in the way things taste If any of these become troublesome, speak with your doctor

Important: If you develop diarrhoea, contact your doctor for advice before taking any more doses.

If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist for advice.

  • Keep all medicines out of the reach and sight of children.
  • Store in a cool, dry place, away from direct heat and light.

  • If you buy any medicines check with a pharmacist that they are safe to take with your other medicines.
  • Never take more than the prescribed dose. If you suspect that you or someone else has taken an overdose of this medicine go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep out of date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.

Further reading & references

  • British National Formulary; 62nd Edition (Sep 2011) British Medical Association and Royal Pharmaceutical Society of Great Britain, London
  • Manufacturer's PIL, DalacinĀ® C 75mg & 150mg Capsules; Manufacturer's PIL, DalacinĀ® C 75mg & 150mg Capsules, Pharmacia Limited, electronic Medicines Compendium. Dated April 2010.
Original Author: Helen Allen Current Version:
Last Checked: 20/04/2011 Document ID: 3615  Version: 24 © EMIS

Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. EMIS has used all reasonable care in compiling the information but make no warranty as to its accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. For details see our conditions.

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