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Cilazapril
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About cilazapril
| Type of medicine | ACE (angiotensin converting enzyme) inhibitor |
| Used for | Hypertension (high blood pressure) Heart failure (where the heart is unable to pump blood efficiently) |
| Also called | Vascace® |
| Available as | Tablets |
Cilazapril works by causing blood vessels to relax. This lowers blood pressure and increases the supply of blood and oxygen to the heart.
Before taking cilazapril
Before taking cilazapril make sure your doctor or pharmacist knows:
- If you are pregnant, trying for a baby or breast-feeding.
- If you suffer from kidney or liver disease.
- If you suffer from ascites (a build up of fluid in the abdomen).
- If you suffer from a collagen vascular disease, such as systemic lupus erythematosus (SLE) or scleroderma.
- If you are on a salt restricted diet or use salt substitutes which contain potassium.
- If you have cardiomyopathy (cardiac muscle disease), poor circulation, or aortic stenosis (narrowing of the blood vessel from the heart).
- If you have atherosclerosis (the build up of fatty deposits on the walls of arteries).
- If you are having dialysis, LDL apheresis (the removal of cholesterol from the blood by a machine) or desensitisation treatment for bee and wasp stings.
- If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
- If you have ever had an allergic reaction to this or any other medicine.
How to take cilazapril
- Before beginning treatment, read the manufacturer's printed information leaflet.
- Take your medication exactly as directed by your doctor.
- Try to take cilazapril at the same time each day to avoid missing any doses. It is best if you take them in the morning with a drink of water.
- If you forget to take a dose, take one as soon as you remember unless it is nearly time for your next dose. Do not take two doses on the same day to make up. If in doubt, speak to your pharmacist or doctor.
Getting the most from your treatment
- If you are having any treatment like an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking.
- Keep your regular doctor's appointment so your progress can be monitored.
- Treatment with cilazapril is usually life-long. Do not stop taking this medicine without speaking to your doctor first.
- If you buy any medicines, check with a pharmacist that they are safe to take with cilazapril.
Can cilazapril cause problems?
Along with their useful effects all medicines can cause unwanted side effects, which usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side effects continue or become troublesome.
| Common side-effects - these affect less than 1 in 10 people who take this medicine | What can I do if I experience this |
| Light-headedness or dizziness when getting up from a sitting or lying position especially the first time you take it | Getting up slowly should help. If you begin to feel dizzy, lie down so that you do not faint, then sit for a few moments before standing. If this continues, speak with your doctor |
| Headache | Ask your pharmacist to recommend a suitable pain-killer. If the headache continues, speak with your doctor |
| Feeling or being sick, stomach pain, diarrhoea | Eat little and often and drink plenty of water to replace any lost fluids |
| Constipation | Try to eat a well balanced diet containing plenty of fibre and drink 6-8 glasses of water each day |
| Dry cough | Speak with your doctor if this is troublesome |
| Tiredness | Make sure your reactions are normal before driving, operating machinery or doing other jobs which could be dangerous if you were not fully alert |
| 'Pins and needles', muscle and joint pain, skin rash, itching, changes in taste, sinusitis, a blocked or runny nose, sore throat, hair loss, and an increased sensitivity to sunlight | Speak with your doctor if any of these are troublesome |
If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.
How to store cilazapril
- Keep all medicines out of the reach of children.
- Store in a cool, dry place, away from direct heat and light.
Important information about all medicines
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References
- Manufacturer's PIL, Vascace®, Roche Products Ltd, electronic Medicines Compendium. January 2008, accessed 22 June 2008.
- British National Formulary; 55th Edition (March 2008) British Medical Association and Royal Pharmaceutical Society of Great Britain, London (link to current BNF).
The authors and editors of this article are employed to create accurate and up to date content reflecting reliable research evidence, guidance and best clinical practice. They are free from any commercial conflicts of interest. Find out more about updating.
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