Cefpodoxime

  • Before taking cefpodoxime, make sure your doctor knows if you have ever had an allergic reaction to any other antibiotic.
  • Take cefpodoxime at regular intervals and complete the course your doctor has prescribed for you.
Type of medicine Cephalosporin antibiotic
Used for Infections such as urinary tract, chest, and skin infections
Also called Orelox®
Available as Tablets and oral liquid

Cefpodoxime is a broad spectrum antibiotic which means it is active against a wide variety of bacteria. It treats infections by killing or stopping the growth of the bacteria that cause them.

Before taking cefpodoxime make sure your doctor or pharmacist knows:

  • If you are pregnant or breast-feeding.
  • If you have kidney problems.
  • If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
  • If you have ever had an allergic reaction to this or any other medicine. It is particularly important that you tell your doctor if you are allergic to any other antibiotics.
  • Before beginning treatment, read the manufacturer's printed information leaflet from inside the pack.
  • Take cefpodoxime exactly as your doctor has told you. It is usually taken twice each day.
  • Take cefpodoxime at regular intervals and complete the prescribed course. It is important to take the full course (even if you feel your infection has cleared up) to prevent the infection from coming back.
  • Take your doses with or after a meal.
  • Avoid taking indigestion remedies at the same time of day as cefpodoxime. This is because antacids can interfere with the way cefpodoxime is absorbed by your body.
  • Try to take cefpodoxime at the same times each day to avoid missing any doses.
  • If you forget to take a dose, take it as soon as you remember unless it is nearly time for your next dose, in which case leave out the missed dose. Do not take two doses together to make up for a forgotten dose.
  • Some people develop thrush (redness and itching in the mouth or vagina) after taking a course of antibiotics. If you think you have thrush speak with your doctor or pharmacist for advice.
  • If you are using oral combined hormonal contraception (the 'pill'), additional contraceptive precautions such as condoms are not required during a course of this antibiotic unless you are sick or have diarrhoea. If you need further advice, speak with your doctor or pharmacist.
  • If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking cefpodoxime.
  • This antibiotic may stop the oral typhoid vaccine from working. If you are having any vaccinations, make sure the person treating you knows that you are taking this medicine.
  • If you buy any medicines, check with a pharmacist that they are safe to take with cefpodoxime.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. These usually improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.

Common side-effects What can I do if I experience this
Diarrhoea Drink plenty of water to replace lost fluids. If the diarrhoea is severe or lasts for more than 24 hours, see your doctor
Feeling or being sick, stomach ache Eat little and often and stick to simple or bland foods
Headache Ask your pharmacist to recommend a suitable painkiller. If the headache continues, speak with your doctor
Dizziness Make sure your reactions are normal before driving, operating machinery or doing any other jobs that could be dangerous if you were not fully alert
Thrush, skin rash and itching Speak with your doctor or pharmacist for advice

Important: If you experience any of the following symptoms, stop taking cefpodoxime and contact your doctor for advice straight away:

  • A severe skin rash.
  • Jaundice, fever, and pain in your joints.
  • Swelling of your tongue, mouth, or face.
  • Severe diarrhoea.

If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.

  • Keep all medicines out of the reach and sight of children.
  • Store in a cool, dry place, away from direct heat and light.
  • Keep the oral liquid in a refrigerator and remember to check the expiry date on the bottle - do not use it after this date.

  • Never take more than the prescribed dose. If you suspect that you or someone else has taken an overdose of this medicine, go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep out of date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.

Further reading & references

Original Author: Helen Allen Current Version:
Last Checked: 07/06/2011 Document ID: 3610  Version: 22 © EMIS

Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. EMIS has used all reasonable care in compiling the information but make no warranty as to its accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. For details see our conditions.

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