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Calcipotriol

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  • Apply once or twice daily to the areas affected by psoriasis.
  • Remember to wash your hands well after each application to prevent accidentally using it on normal skin.

About calcipotriol

Type of medicine Vitamin D analogue
Used for Plaque psoriasis
Also called Dovonex®
Available as Cream, ointment and scalp solution

Calcipotriol is used to treat plaque psoriasis. It is similar to vitamin D, a vitamin essential for healthy skin.

Plaque psoriasis is a skin disorder caused by cells in the outer layer of the skin multiplying too quickly. As new skin cells are produced the old ones are shed. If this process is taking place too quickly, old skin cells build up on the skin surface causing red, scaly patches. Calcipotriol helps to control psoriasis by slowing down the production of new skin cells.

Before using calcipotriol

Before using calcipotriol make sure your doctor or pharmacist knows:

  • If you are pregnant, trying for a baby or breast-feeding.
  • If you have been told you have high calcium levels in your blood or problems processing calcium.
  • If you have a type of psoriasis other than plaque psoriasis (such as generalised pustular or erythrodermic exfoliative psoriasis).
  • If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
  • If you have ever had an allergic reaction to this or any other medicine.
  • Calcipotriol cream is not for use in children under 6 years of age, and the ointment and scalp application are not for use in anyone under the age of 18 years.

How to use calcipotriol

  • Before beginning treatment, read the manufacturer's printed information leaflet.
  • Apply this preparation exactly as your doctor has told you to.
  • Apply the ointment or cream once or twice each day by rubbing it gently into the affected areas. Wash your hands well after each application to avoid accidentally using it on other areas of your body. Do not apply it near the eyes, face, or mouth.
  • You only need to use a small amount of cream or ointment. One fingertip unit (a line from the tip of an adult index finger to the first crease) is enough to cover an area twice the size of an adult hand.
  • Do not use more than 100 grams a week if you are an adult, more than 75 grams a week in children over 12 years of age, or more than 50 grams a week in children between the ages of 6-12 years.
  • If you have been given the scalp solution, apply it twice daily (once in the morning and once in the evening) unless your doctor has told you otherwise. Squeeze a few drops of the solution onto the parts of your scalp that are affected, and then rub it in gently. You only need to use a small amount. Two drops cover an area the size of a postage stamp. Remember to wash your hands after using the solution.

Getting the most from your treatment

  • Your skin may become more sensitive to sunlight while you are being treated with this preparation. Avoid sun beds and sitting out in the sun, and if necessary use a sun cream higher than factor 15.
  • If your symptoms do not begin to improve after using this preparation for 2-4 weeks or if they get worse, tell your doctor.
  • If you are using calcipotriol with UV light therapy, you must apply it at least two hours before the light treatment.
  • Keep your regular doctor's appointment so your progress can be monitored.

Can calcipotriol cause problems?

Along with their useful effects all medicines can cause unwanted side effects, which usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side effects continue or become troublesome.

Common side-effects - these affect less than 1 in 10 people who use this medicine What can I do if I experience this
Skin irritation, redness Speak to your doctor if this is troublesome

Important: If you experience constipation with poor appetite and sickness, speak with your doctor immediately or go to your local accident and emergency department without delay.

If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.

How to store calcipotriol

  • Keep all medicines out of the reach and sight of children.
  • Store in a cool, dry place, away from direct heat and light.

Important information about all medicines


  • If you buy any medicines, check with a pharmacist that they are safe to take with your other medicines.
  • If you are having any treatment like an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking.
  • If you suspect that you or someone else has swallowed some of this medicine, go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep out of date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.

References

  • Manufacturer's PIL, Dovonex® Cream, Leo Laboratories, electronic Medicines Compendium. Revised June 2006, accessed 17 June 2008.
  • Manufacturer's PIL, Dovonex® Scalp Solution, Leo Laboratories, electronic Medicines Compendium. Revised May 2007, accessed 17 June 2008.
  • British National Formulary; 55th Edition (March 2008) British Medical Association and Royal Pharmaceutical Society of Great Britain, London.
Comprehensive patient resources are available at www.patient.co.uk
© EMIS 2008 DocID: 3213 DocRef: dils2054 Last Reviewed: 25 Nov 2008 Version: 22

The authors and editors of this article are employed to create accurate and up to date content reflecting reliable research evidence, guidance and best clinical practice. They are free from any commercial conflicts of interest. Find out more about updating.

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