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Calcipotriol and Betamethasone

  • Apply a thin layer once daily to the affected areas.
  • This preparation should not be used on broken or infected skin.

About calcipotriol and betamethasone

Type of medicineTopical preparation for psoriasis
Used forPsoriasis
Also calledDovobet®
Xamiol®
Available asOintment and gel

This preparation contains two ingredients, calcipotriol and betamethasone. It is used to treat psoriasis and although it is not a cure for this condition, it will help relieve the symptoms.

Psoriasis is a skin disorder caused by cells in the outer layer of the skin (the epidermis) multiplying too quickly. As new skin cells are produced, old ones are shed. If this process is taking place too quickly, old skin cells build up on the skin surface causing red, scaly patches.

The betamethasone ingredient relieves inflammation when the skin is red, swollen and irritated.

Before using calcipotriol and betamethasone

Before using calcipotriol and betamethasone make sure your doctor or pharmacist knows:

  • If you are pregnant, trying for a baby or breast-feeding.
  • If you have been told you have high calcium levels in your blood or problems processing calcium.
  • If you have a type of psoriasis other than plaque psoriasis (such as generalised pustular or erythrodermic exfoliative psoriasis).
  • If you have areas of infected skin.
  • If you suffer from acne rosacea.
  • If you suffer from perioral dermatitis (skin rash around the mouth).
  • If you suffer from a liver or kidney disorder.
  • If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
  • If you have ever had an allergic reaction to this or any other medicine.
  • This preparation is not usually recommended for use in anyone under 18 years of age.

How to use calcipotriol and betamethasone

  • Before beginning treatment, read the manufacturer's printed information leaflet.
  • Use this preparation exactly as directed by your doctor.
  • Apply once each day by rubbing it gently into the affected areas. Wash your hands well after each application to avoid accidentally using it on other areas of your body.
  • If you are using the ointment, do not apply it near the eyes, face, mouth or scalp. You only need to use a small amount. One fingertip unit (a line of ointment from the tip of an adult index finger to the first crease) is enough to cover an area twice the size of an adult hand.
  • If you are using the gel, apply it to the scalp only. Shake the bottle before using it and allow it to remain on the scalp during the day or overnight before washing your hair.
  • The treatment period usually lasts no longer than 4 weeks.
  • Never use more than 15 grams a day or more than 100 grams a week, and do not apply it to more than a third of the surface area of your body.
  • Do not use calcipotriol and betamethasone on thin or broken areas of skin and you must not cover any treated areas with bandages or dressings.

Getting the most from your treatment

  • If your symptoms do not begin to improve after using this preparation for 2-4 weeks or if they get worse, tell your doctor.
  • If your skin becomes infected you must tell your doctor as you may need to stop using this preparation.
  • Treated areas of your skin may become more sensitive to sunlight while you are using this preparation. Avoid sun beds and sitting out in the sun, and if necessary use a sun cream higher than factor 15.
  • Stopping using this preparation suddenly can cause problems such as 'flare up'. Your doctor may advise you to reduce the amount you use gradually.
  • Keep your regular doctor's appointment so your progress can be monitored.

Can calcipotriol and betamethasone cause problems?

Along with their useful effects, all medicines can cause unwanted side effects which usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side effects continue or become troublesome.

Common side-effects - these affect less than 1 in 10 people who use this medicineWhat can I do if I experience this
Skin irritation, itching, rash, burning sensationSpeak to your doctor if this is troublesome

Important: If you experience constipation with poor appetite and sickness, speak with your doctor immediately or go to your local accident and emergency department without delay.

If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.

How to store calcipotriol and betamethasone

  • Keep all medicines out of the reach and sight of children.
  • Store in a cool, dry place, away from direct heat and light.

Important information about all medicines


  • If you buy any medicines, check with a pharmacist that they are safe to take with your other medicines.
  • If you are having any treatment like an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking.
  • If you suspect that you or someone else has swallowed some of this medicine, go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep out of date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.

References

  • Manufacturer's PIL, Dovobet®, Leo Laboratories Ltd. electronic Medicines Compendium. Approved June 2007, accessed 16 June 2008.
  • Manufacturer's PIL, Xamiol®, Leo Laboratories Limited, electronic Medicines Compendium. Dated September 2008, accessed November 2008.
  • British National Formulary; 56th Edition (September 2008) British Medical Association and Royal Pharmaceutical Society of Great Britain, London (link to current BNF).
Comprehensive patient resources are available at www.patient.co.uk
© EMIS 2008DocID:
3824
DocRef:
dils3839
Last Reviewed:
17 Nov 2008
Version:
22
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