Benzydamine for sore mouth/throat

  • Benzydamine eases painful conditions of your mouth or throat.
  • If you do not feel the pain has eased after using it for seven days, see your doctor for further advice.
  • The oral rinse (mouthwash) is not suitable for children under 12 years of age.
Type of medicine Anti-inflammatory analgesic
Used for Painful mouth and throat conditions such as mouth ulcers and sore throat
Also called Difflam®
Available as Mouthwash or spray

Benzydamine reduces pain and inflammation associated with painful mouth and throat conditions. It works by stopping the formation of prostaglandins which are chemicals that are produced where there is inflammation. Reducing these chemicals, reduces the discomfort associated with a sore throat or mouth, and eases pain.

Benzydamine is available on prescription or you can buy it at pharmacies, without a prescription.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking benzydamine it is important that your doctor, dentist or pharmacist knows:

  • If you are pregnant, trying for a baby or breast-feeding.
  • If you have ever had an allergic reaction to this or to any other medicine.
  • If you are taking other medicines, including those available to buy without a prescription, herbal and complementary medicines.
  • Before you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The leaflet will give you more information about the specific brand of benzydamine you have been given, and a full list of possible side-effects from using it.
  • If you are using the oral rinse, use 15 ml (half a measure) as a mouthwash every 1½-3 hours to help ease your pain. After you have gargled with it, spit it out - try not to swallow benzydamine. If you find the mouthwash causes some stinging, dilute it with the same amount of water before you use it. This oral rinse is not suitable for children under 12 years of age to use.
  • If you are using the spray, use 4-8 sprays on to the sore area every 1½-3 hours. This is the dose for adults. If you are giving benzydamine to your child, check the label carefully to make sure you are using the correct number of sprays for the age of your child.

    How to use the spray:
    • Hold the bottle upright.
    • Lift the nozzle of the spray away from the container until it is horizontal.
    • If it is the first time you have used the spray, point the nozzle away from you and press down on the green plunger on the top of the container until you see a fine mist. The spray is now ready to use.
    • Aim the spray at the sore area of your mouth or throat and press down on the green plunger to release one spray. Repeat this step to give the correct number of sprays.
    • After each use, push the nozzle of the spray back down against the container to store it until next time.
  • You should expect the soreness to have eased within seven days of using benzydamine. If there is no improvement after this time, see your doctor for advice.
  • If you are using the spray, be careful not to get it into your eyes. If this does happen, rinse it out of your eye with water.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. These usually improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.

Occasional benzydamine side-effects What can I do if I experience this?
Numbness or stinging in your mouth If you are using the mouthwash, dilute it with some water
  • Keep all medicines out of the reach and sight of children.
  • Store in a cool, dry place, away from direct heat and light.
  • If you buy any medicines check with a pharmacist that they are safe to take with your other medicines.
  • Never take more than the prescribed dose. If you suspect that someone has taken an overdose of this medicine, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.
  • If you are having an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.

Further reading & references

  • British National Formulary; 62nd Edition (Sep 2011) British Medical Association and Royal Pharmaceutical Society of Great Britain, London
  • Manufacturer's PIL, Difflam® oral rinse; Manufacturer's PIL, Difflam® oral rinse, Meda Pharmaceuticals, The electronic Medicines Compendium. Dated March 2010.
  • Manufacturer's PIL, Difflam® spray; Manufacturer's PIL, Difflam® spray, Meda Pharmaceuticals, The electronic Medicines Compendium. Dated March 2010.
Original Author: Helen Allen Current Version: Peer Reviewer: Dr Hannah Gronow
Last Checked: 18/04/2012 Document ID: 3322  Version: 24 © EMIS

Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. EMIS has used all reasonable care in compiling the information but make no warranty as to its accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. For details see our conditions.

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