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Antihistamines (topical)

Post your experience
  • Do not use this cream for more than three days at a time.
  • If your symptoms do not improve, stop using the cream and ask your pharmacist or doctor for advice.

About topical antihistamines

Type of medicine Topical antihistamine
Used for Itchy skin
Also called Anthisan®, Anthisan® Bite and Sting, Benadryl® Skin Allergy Relief
Available as Cream

Exposure to irritant substances can cause the body to produce a chemical called histamine. The release of histamine causes allergic symptoms which can include itching and swelling. Antihistamines reduce the effects of histamine and help to relieve these symptoms. They are effective when taken by mouth as tablets, but antihistamine creams (topical antihistamines) are also available to apply to the skin and can be used for short periods of time.

Some topical antihistamines preparations also contain camphor to help cool the skin and zinc oxide to help reduce the itching.

Before using topical antihistamines

Before using topical antihistamines make sure your doctor or pharmacist knows:

  • If you are pregnant, trying for a baby or breast-feeding.
  • If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
  • If you have ever had an allergic reaction to this or any other medicine.

How to use topical antihistamines

  • Before beginning treatment, read the instructions on the container and the manufacturer's printed information leaflet.
  • Apply the cream to the affected area as detailed on the container.
  • Do not use this preparation for more than three days at a time. If your symptoms do not begin to improve during this time, or if they get worse, ask your pharmacist or doctor for further advice.

Getting the most from your treatment

  • Do not apply this cream to broken, raw, or weeping skin including eczema, cuts and grazes.
  • Do not allow this preparation to come into contact with the eyes or mucous membranes (for instance, inside the mouth, vagina, or inside the nostrils).
  • Do not sit in the sun or use sunbeds while you are using this preparation.
  • The following can make your itching worse and are best avoided: changes of temperature, wearing rough or irritating clothing (such as wool), and drinking alcohol.

Can topical antihistamines cause problems?

Topical antihistamines occasionally cause allergic skin reactions such as redness, itching, or a burning sensation. If this occurs, stop using the cream and ask your pharmacist or doctor for advice.

If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.

How to store topical antihistamines

  • Keep all medicines out of the reach of children.
  • Store in a cool, dry place, away from direct heat and light.

Important information about all medicines


  • If you are having any treatment like an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking.
  • If you suspect that you or someone else has swallowed some of this medicine, go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep out of date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.

References

  • British National Formulary; 55th Edition (March 2008) British Medical Association and Royal Pharmaceutical Society of Great Britain, London.
Comprehensive patient resources are available at www.patient.co.uk
© EMIS 2009 DocID: 3323 DocRef: dils2280 Last Reviewed: 11 Jul 2008 Version: 23

The authors and editors of this article are employed to create accurate and up to date content reflecting reliable research evidence, guidance and best clinical practice. They are free from any commercial conflicts of interest. Find out more about updating.

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