Antazoline and xylometazoline eye drops

  • These drops are used to treat red, watery, itchy eyes caused by allergies such as hay fever.
  • Use one drop two or three times a day in both eyes. Do not use the drops for more than seven days.
  • When first put in, eye drops may cause blurred vision. Wait until this clears before you drive.
Type of medicine Anti-inflammatory eye drops
Used for Relieving the eye symptoms of allergies such as hay fever
Also called Otrivine-Antistin®
Available as Eye drops

Allergic conjunctivitis causes red, watery, itchy eyes. The common cause is an allergy to pollen in the hay fever season. Other causes are less common, such as allergies to house dust mite, cosmetics, and problems with contact lenses. These eye drops relieve the symptoms of allergic conjunctivitis by blocking the action of a chemical called histamine, which is involved in the allergic reaction. They are available on prescription, or you can buy them at pharmacies, without a prescription.

To make sure this is the right treatment for you, before you start using these eye drops it is important that your doctor or pharmacist knows:

  • If you wear soft contact lenses.
  • If you are pregnant or breast-feeding.
  • If you have glaucoma (increased pressure in your eye).
  • If the drops are intended for a child under 12 years of age. Antazoline and xylometazoline eye drops are not recommended for this age group.
  • If you have ever had an allergic reaction to any eye drops.
  • If you are taking other medicines, including those available to buy without a prescription, herbal and complementary medicines.
  • First wash your hands.
  • Remove the cap from the bottle.
  • Tilt your head back a little and pull the lower lid of your eye downwards to form a pocket.
  • Hold the bottle upside down near to your eye. Try not to touch your eye as you do this.
  • Apply enough pressure to the bottle to release one drop into your eye.
  • Close your eye for a minute or two, and press gently on the side of your nose where the corner of your eye meets your nose. This helps to stop the drop from draining away and keeps it in your eye.
  • Repeat the process in your other eye.
  • Replace the cap.
  • Before using these eye drops, read the manufacturer's printed information leaflet. The leaflet will give you more information about antazoline and xylometazoline, and a full list of possible side-effects from using the drops.
  • Use the drops two or three times each day into both eyes. Try to use the drops at regular intervals and try not to miss any doses. Do not use the drops for more than seven consecutive days.
  • Take care not to touch your eye, fingers, or any other surface with the dropper of the bottle. This could contaminate the drops left in the bottle.
  • When first put in, these eye drops may cause blurred vision. This should quickly clear, but make sure you can see properly before you drive, use machines or do any other jobs which would be dangerous if you were unable to see clearly.
  • If your symptoms do not improve within two days, or if they become worse, check with your doctor.
  • If you are using any other eye drops or ointments, leave about ten minutes between applying each one.
  • Do not wear soft contact lenses while you are using these eye drops. This is because there is a preservative in the drops which may affect soft contact lenses.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. These usually improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.

Side-effects which may occur What can I do if I experience this?
Mild eye irritation such as burning or stinging, blurred vision These usually disappear within a few minutes of applying the eye drops. Do not drive or use tools or machines until your vision is clear

If you experience any other symptoms which you think may be due to these eye drops, speak with your doctor or pharmacist.

  • Keep all medicines out of the reach and sight of children.
  • Store in a cool, dry place, away from direct heat and light.
  • Eye drops only keep for four weeks once the bottle has been opened so throw away the bottle after this time, even if there is some solution left. Never keep opened bottles of eye drops to use later. This will help to prevent the risk of eye infections.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • If you buy any medicines, check with a pharmacist that they are safe to use with your other medicines.
  • If you suspect that someone has swallowed some of this medicine, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.
  • If you are having an operation or dental treatment, tell the person carrying out the treatment which medicines you are using.
  • Never keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.

Further reading & references

  • British National Formulary; 63rd Edition (Mar 2012) British Medical Association and Royal Pharmaceutical Society of Great Britain, London
Original Author: Helen Allen Current Version: Peer Reviewer: Dr Adrian Bonsall
Last Checked: 18/05/2012 Document ID: 3719  Version: 24 © EMIS

Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. EMIS has used all reasonable care in compiling the information but make no warranty as to its accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. For details see our conditions.

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