Acetylcysteine for dry eyes

  • These drops act as artificial tears.
  • Your vision may be blurred immediately after using the drops. Do not drive unless your vision is clear.
  • Do not wear soft contact lenses while you are using these eye drops unless your doctor has told you otherwise.
Type of medicine Eye lubricant
Used for Dry eyes
Also called Ilube®
Available as Eye drops

Acetylcysteine works by reducing the stickiness of tears. In the brand Ilube®, it is combined with an ingredient called hypromellose which soothes and lubricates the surface of the eye. These two ingredients together act as artificial tears to help ease dryness and soreness associated with some dry eye conditions, particularly where the dryness is caused by a reduced flow of tears.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start using acetylcysteine eye drops it is important that your doctor or pharmacist knows:

  • If you are pregnant, trying for a baby or breast-feeding.
  • If you have ever had an allergic reaction to acetylcysteine or to a preservative in any other eye drops.
  • If you wear soft contact lenses.
  • Wash your hands before you use the drops.
  • Remove the plastic disc, metal ring and rubber bung from the top of the bottle. Take the plastic dropper from the packet and push it on to the bottle. Unscrew the plastic cap.
  • Tilt your head back a little and pull your lower eyelid down to form a pocket between your eyelid and eye.
  • Bring the dropper near to your eye. Try not to touch your eye as you do this.
  • Gently squeeze to release one drop. Only if you think that you have missed your eye should you release a second drop.
  • Close your eye for a minute or two, and press gently on the side of your nose where the corner of your eye meets your nose. This helps to stop the drop from draining away and keeps it in your eye.
  • If you need to use the drops in both eyes, repeat the above steps for your other eye.
  • Replace the cap.
  • Wash your hands again.
  • Before you start using these eye drops, read the manufacturer's printed information leaflet from inside the pack.
  • Use one drop into the eye (or eyes) affected by dryness. You can do this 3 or 4 times each day unless you have been told otherwise by your doctor.
  • Take care not to touch your eye, fingers, or any other surface with the dropper of the bottle. This could contaminate the drops left in the bottle.
  • If you forget to use the drops at the correct time, do not worry, just use them when you remember. Do not double up to make up for a missed dose.
  • If you are using any other eye drops or ointments, leave about ten minutes between applying each one.
  • When first put in, these eye drops may cause blurred vision. This should quickly clear. Make sure you can see clearly before you drive, use machines or do any other jobs which could be dangerous if you were unable to see properly.
  • Do not wear soft contact lenses while you are using these eye drops unless your doctor has advised you otherwise. This is because there is a preservative in the drops which can affect soft contact lenses.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. These usually improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.

Possible acetylcysteine eye drop side-effects What can I do if I experience this?
Eye irritation or redness If this continues, speak with your doctor for advice

If you experience any other symptoms which you think may be due to these eye drops, discuss them with your doctor or pharmacist.

  • Keep all medicines out of the reach and sight of children.
  • Store in a cool, dry place, away from direct heat and light.
  • Eye drops only keep for four weeks once the bottle has been opened, so do not use these drops if the bottle has been open for longer than this. This will help to prevent the risk of eye infections.
  • Make sure that the person prescribing this medicine knows about any other medicines that you are taking. This includes medicines you buy and herbal and homeopathic medicines.
  • If you buy any medicines check with a pharmacist that they are safe to take with your other medicines.
  • Before taking this medicine tell your doctor if you have ever had an allergic reaction after taking any medicine.
  • Never take more than the prescribed dose. If you suspect that someone has swallowed some of this medicine, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.
  • If you are having an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.

Further reading & references

  • British National Formulary; 62nd Edition (Sep 2011) British Medical Association and Royal Pharmaceutical Society of Great Britain, London
  • Manufacturer's PIL, IlubeĀ® Eye Drops; Manufacturer's PIL, IlubeĀ® Eye Drops, Moorfields Pharmaceuticals, The electronic Medicines Compendium. Dated September 2010.
Original Author: Helen Allen Current Version: Peer Reviewer: Prof Cathy Jackson
Last Checked: 18/04/2012 Document ID: 3656  Version: 25 © EMIS

Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. EMIS has used all reasonable care in compiling the information but make no warranty as to its accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. For details see our conditions.

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