Acarbose

  • Take acarbose tablets at the beginning of your meal. They can be chewed with your first mouthful of food or swallowed with a drink of water.
  • Remember to follow any advice you have been given about your diet and taking exercise.
  • Common side-effects are flatulence (wind) and diarrhoea. These usually reduce as your body adjusts.
Type of medicine Antidiabetic medicine
Used for Type 2 diabetes mellitus
Also called Glucobay®
Available as Tablets

Insulin is a hormone that is made naturally in your body. It helps to control the levels of sugar in your blood. If your body does not make enough insulin to meet its needs, or if it does not use the insulin it makes effectively, this results in the condition called diabetes mellitus (sugar diabetes).

People with diabetes need treatment to control the amount of sugar in their blood. This is because good control of blood sugar levels reduces the risk of complications later on. Some people can control the sugar in their blood by making changes to the food they eat but, for other people, medicines like acarbose are given alongside the changes in diet.

Acarbose works by slowing down the digestion and absorption of sugars and starches from your digestive system. This helps to reduce the high blood sugar levels which occur after eating meals.

Before taking acarbose make sure your doctor or pharmacist knows:

  • If you are pregnant, trying for a baby or breast-feeding.
  • If you are under 18 years of age.
  • If you have liver or kidney problems.
  • If you have a hernia or have had surgery recently on your abdomen.
  • If you have inflammatory bowel disease or have ever had a blockage in your bowel.
  • If you are taking other medicines, including those available to buy without a prescription, herbal and complementary medicines.
  • If you have ever had an allergic reaction to this or to any other medicine.
  • Before starting this treatment, read the manufacturer's printed information leaflet from inside the pack.
  • Take acarbose exactly as your doctor has told you.
  • You can swallow acarbose tablets with a drink of water just as you start eating a meal, or if you prefer, you can chew the tablets with your first mouthful of food.
  • When starting this treatment, your doctor will give you a small dose and then gradually increase the dose. This allows your doctor to make sure that you have the dose that helps your condition and avoids any unwanted symptoms.
  • If you forget to take a dose, do not worry, just take the next dose as normal. Do not take two doses together to make up for a forgotten dose.
  • It is important that you keep your regular doctor's and clinic appointments. This is so your progress can be monitored. You are likely to need regular check-ups with an eye clinic and a foot clinic as well as with your doctor and diabetes clinic.
  • Your doctor may recommend that you test for sugar in your blood or urine regularly to check that your diabetes is being controlled. Your doctor or diabetes nurse will show you how to do this.
  • If you have been given advice by your doctor about changes to your diet, stopping smoking or taking regular exercise, it is important for you to follow the advice you have been given.
  • Check with your doctor before taking up any new physical exercise, as this will have an effect on your blood sugar levels and you may need to check your blood or urine levels more regularly.
  • Drinking alcohol may affect the control of your blood sugar. If you have a drink, keep to the recommended alcohol limits.
  • If you are due to have an operation or dental treatment, you should tell the person carrying out the treatment that you have diabetes.
  • If you get unusually thirsty, pass urine more frequently, and feel very tired, then let your doctor know. These are signs that there is too much sugar in your blood and your treatment may need adjusting.
  • Make sure you know what it feels like if your blood sugar is too low. This is known as hypoglycaemia or a 'hypo'. The first signs of hypoglycaemia are: feeling shaky or anxious, sweating, looking pale, feeling hungry, having palpitations (a feeling that your heart is pounding), and feeling dizzy. If these happen you should eat or drink something containing glucose straightaway. Your pharmacist will be able to recommend a suitable glucose preparation for you.
  • If you are a driver you should take special care, as your ability to concentrate may be affected if your diabetes is not well-controlled. Make sure you know what it feels like if your blood sugar is low. You may be advised to check your blood or urine glucose levels before you travel and have a snack with you on long journeys.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. These usually improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.

Common acarbose side-effects What can I do if I experience this?
Flatulence, wind, abdominal pain Usually these symptoms reduce as your body adjusts. Keep to any advice you have been given about your diet
Diarrhoea, soft stools Try to avoid sugar and sucrose-containing foods. Drink plenty of water to replace lost fluids

If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.

  • Keep all medicines out of the reach and sight of children.
  • Store in a cool, dry place, away from direct heat and light.
  • If you buy any medicines check with a pharmacist that they are safe to take with your other medicines.
  • Never take more than the prescribed dose. If you suspect that someone has taken an overdose of this medicine, go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.

Further reading & references

  • British National Formulary; 62nd Edition (Sep 2011) British Medical Association and Royal Pharmaceutical Society of Great Britain, London
  • Manufacturer's PIL, Glucobay® 50 mg tablets; Manufacturer's PIL, Glucobay® 50 mg tablets, Bayer plc, electronic Medicines Compendium. Dated May 2010.
Original Author: Monica Kapoor Current Version: Peer Reviewer: Prof Cathy Jackson
Last Checked: 15/12/2011 Document ID: 3474  Version: 24 © EMIS

Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. EMIS has used all reasonable care in compiling the information but make no warranty as to its accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. For details see our conditions.

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