Nuts and peanuts can cause allergic reactions, which are sometimes severe. A severe reaction to nuts is called anaphylaxis and can be life-threatening. Symptoms often start quickly, within an hour of coming into contact with a nut, and sometimes within minutes. Avoiding foods that contain nuts will prevent an allergic reaction. But, if you do come into contact with nuts, and a reaction starts, then treating it quickly will help to minimise the risks to you. If you have a severe allergic reaction, if available, give yourself an adrenaline injection straightaway and call an ambulance. If you are well prepared and take action quickly the risk of suffering any serious problems is small.
What is nut allergy?
An allergy occurs when your body's immune system, which normally fights infection, overreacts to a substance called an allergen. Most allergens are not obviously harmful and they have no effect on people who are not allergic to them. Allergic reactions to allergens can vary from mild to life-threatening.
Both peanuts and tree nuts (for example, walnuts, hazelnuts, almonds, cashews, pecans, brazils and pistachios) can act as allergens, and can cause an allergic reaction in some people. When you come into contact with something that you are allergic to (an allergen), a group of cells in your body called mast cells release a substance called histamine. Histamine causes the tiny blood vessels in the tissues of your body to leak fluid which causes the tissues to swell. This results in a number of different symptoms.
Strictly speaking, peanuts are not nuts, they are legumes - they grow underground whereas other nuts grow on trees. The word nut in this article can mean either tree nuts or peanuts.
What causes nut allergy?
If you are allergic to nuts, when you first come into contact with nuts your immune system reacts and prepares to fight. However, you don't get any symptoms of a reaction. It is only when you come into contact with nuts for a second time that a full allergic reaction happens. Most children who are allergic to nuts have the symptoms of an allergic reaction when they appear to be exposed to nuts for the first time. However, this is probably not their first exposure, but their second. They may already have come into contact with nuts through their mother - either whilst they were in the womb or through breast milk if they were breast-fed.
Most people with nut allergy react after contact with small amounts (less than one nut) and some people may react to trace amounts. This means that you don't always have to eat nuts to have a reaction. A few people are so sensitive to nut allergens that a tiny amount on their lips, or even standing next to someone eating peanuts, can be enough to start a reaction.
There are lots of different allergens but nuts cause some of the strongest and most severe reactions. Doctors don't yet know why this is.
How common is nut allergy and who gets it?
In the UK about one in 100 people has an allergy to peanuts and about one in 200 people has an allergy to tree nuts. The number of people with peanut allergy is growing.
Nut allergy is the most common type of severe food allergy. It often starts when children are very young. Most first allergic reactions take place when a child is between 14 months and two years old. Unlike other food allergies such as milk allergy, nut allergy is something that you are unlikely to grow out of. Only about one in five people with a nut allergy will grow out of it, and these tend to be the people who have mild reactions.
If you have what is called atopy, or if atopy runs in your family, then you are more at risk of developing an allergy to nuts. Atopy is the name for a group of allergic conditions that include hay fever, asthma and eczema. If you have an allergy to peanuts then you may also react to tree nuts.
What are the symptoms?
Allergic reactions to nuts can vary from mild to very severe, and are sometimes life-threatening. Symptoms often start very quickly, within an hour of having come into contact with a nut, and sometimes within minutes. Reactions that take place more than four hours after coming into contact with nuts are unlikely to be an allergy.
Signs and symptoms of a mild allergic reaction can include:
- Your mouth and lips tingling.
- Your face swelling.
- Feeling sick.
- Urticaria (nettle rash or hives).
- Colicky pains in your abdomen (tummy or stomach).
- A feeling of tightness around your throat.
Signs and symptoms of a more severe allergic reaction can include:
- All of the above.
- Wheezing or difficulty breathing due to an asthma-like attack, or swelling around your throat.
- A sense of impending doom.
- Dilation (opening up) of your blood vessels, which can cause:
- general redness of your skin
- a fast heart rate
- a low blood pressure, which can cause you to feel faint or to collapse
This severe reaction is called anaphylaxis and without quick treatment you would soon become unconscious. A small number of people die every year as a result of this kind of severe reaction, usually because they do not get treatment quickly enough. If you think you are having an anaphylactic reaction you need to call an ambulance straightaway and get immediate medical help.
About one in three people with a nut allergy has an initial reaction to the nut, followed by a second reaction between one and eight hours after the first. This is why it is important to stay in hospital after an initial reaction.
How is nut allergy diagnosed?
Medical history and examination
Your doctor may suspect that you have a nut allergy from your symptoms. Your doctor may then ask a lot of questions. For example, the amount and type of food that you ate which caused a reaction, how quickly the symptoms started, how severe they were, how long they lasted, etc.
Skin prick test
This may be done to help confirm the allergy. For this test, a drop of nut extract solution is placed on the skin, usually on the forearm. Then, a needle prick is made through the drop. This is usually painless as just the very surface of the skin is pricked. However, it is enough to let a tiny amount of solution into your skin. If a reaction occurs, it happens within 20-30 minutes.
- A positive reaction is when the skin under the solution becomes red and itchy. A white, raised swelling called a weal surrounds the red central area. A weal takes about 15-20 minutes to reach its full size, and then fades over a few hours.
- A negative reaction is when the skin remains normal. This means that you are not allergic to the substance in the solution.
Do not take antihistamines on the day of the test as they may dampen any allergic response during the test.
You may also have a blood test called a RAST test or an ELISA test. These measure the amount of a protein called IgE antibody which is produced as a result of an allergic reaction.
If other tests are not conclusive then your doctor may ask you to take part in a food challenge. For this test you are given foods to eat that may or may not contain nuts. You will then be watched closely for 15-30 minutes to see whether you have a reaction. Food challenges are always done at a hospital because of the risk of a severe reaction.
Once an allergy has been confirmed an allergy specialist will usually help you to devise a plan to manage it. This plan will be individual to you and will take into account how severe your reaction is.
What are the treatment options for nut allergy?
Avoid nuts wherever possible
Preventing an allergic reaction from happening in the first place is a key part of living with a nut allergy. So, learn to recognise foods that may contain nuts and avoid them. You may be referred to a dietician to help with this. Advice may include:
1. Check the ingredients:
- Always check food labels, even for products you know, as ingredients can change.
- Avoiding whole nuts is relatively easy. What is more difficult is avoiding nuts in processed foods. Nuts are not always obviously listed on ingredient labels. For example, peanut can be listed as groundnut, earth nut, monkey nut, mixed nuts, peanut butter, peanut oil, arachis oil, and groundnut oil.
- Nuts and nut oils are used as ingredients in a wide range of foods. Take care with biscuits, cakes, pastries, desserts, ice cream, breakfast cereals, cereal bars, nut butters and spreads, confectionery, vegetarian dishes, and salad dressings.
- Chinese, Thai and Indonesian dishes often use nuts and nut oil, particularly peanuts or peanut oil.
- Get a list of nut-free foods from your local supermarket.
2. Take care when you are not preparing your food:
- When eating out, ask staff which foods contain nuts and the risk of contamination of other foods. If possible, speak to the chef, not the waiter or waitress.
- Avoid eating foods at buffets or from delicatessens or bakeries where it is easy for food to be contaminated by touching other foods containing nuts.
- Do not eat anything you are unsure about.
- If friends or family prepare food for you, make sure they know what you can't eat.
- If your child has an allergy to nuts then make sure that they do not share food with other children at parties and other group events. Take food for them.
Principles of treatment
It is unlikely that you will always be able to avoid contact with nuts and you may be accidentally exposed to nuts at any time. So, be prepared:
1. Make sure that you, and others around you like your friends and family, know that you are allergic to nuts and what to do if an allergic reaction starts:
- If your child has a nut allergy then make sure that anyone else who looks after your child knows about it and knows what to do if a reaction starts. For example, nursery staff, babysitters, teachers and other parents.
- You should (or your child should if they have an allergy) wear a MedicAlert® (see below) bracelet or similar, or carry some kind of ID with you that tells other people about your allergy.
2. If an allergic reaction starts, get the right treatment quickly:
- It is vitally important that if an allergic reaction starts you get treatment as quickly as possible. The sooner your reaction is treated, the better.
- Mild reactions can be treated with an antihistamine medicine.
- More serious reactions are treated with adrenaline which, if given quickly, can reverse the symptoms of the reaction.
- Adrenaline is given by an injection so that it can work straightaway. If you have a severe reaction to nuts you will be given an adrenaline injection (like a pen) that you can carry with you all the time. Brand names include EpiPen®, Emerade® and Jext®.
- These adrenaline injections come in different doses for adults and children. They work by injecting adrenaline into your thigh muscle when you press a button or jab it against your skin.
- If you have a severe allergy you must carry your adrenaline injection with you at all times. Some people keep adrenaline in the places where they spend most of their time - for example, at home, at school or at work. Many people carry two injections 'just in case'.
- Check the expiry date on the adrenaline regularly. If it passes the expiry date, get a new one. Also, make sure that you know how to use it properly. Your family and friends should know how to use it too, in case you are not able to.
Know what to do if you have an allergic reaction
1. Mild reactions:
- Take an antihistamine tablet as soon as possible. You can buy these at pharmacies or get them on prescription. Antihistamines block the action of histamine, the chemical released into your body during an allergic reaction. They usually take 15-30 minutes to start working.
- If your reaction gets worse then get medical help straightaway.
2. Severe (anaphylactic) reactions:
- If you have an adrenaline injection pen, use it.
- Get help and call an ambulance straightaway. If possible, always have someone with you at all times if you have a reaction, even if need to go to the toilet (for example, even if you feel sick or are vomiting).
- If you have asthma and have an inhaler, use it.
- In the ambulance or at the hospital you may also be given oxygen to help your breathing, steroids to reduce any inflammation, and antihistamines to counter the allergic reaction.
- Some people may need more intensive treatment if the reaction is very severe.
Mild symptoms can last up to an hour but severe symptoms can last longer. You will need to stay in hospital until your doctor is sure you have fully recovered.
Possible future treatments
Immunotherapy (desensitisation) is a treatment where you are given tiny amounts of the allergen which is then very gradually increased over time. The aim is to build up tolerance to the allergen. This treatment has been used with some success to treat pollen and insect venom allergies. But, at present it is not widely used to treat food allergy such as nut allergy because of the risk of anaphylaxis. However, studies looking at this are underway. For example, the study cited at the end by Blumchen and colleagues.
Can nut allergy be prevented?
In the past, the Department of Health advised that atopic pregnant and breast-feeding mothers and their infants should avoid peanuts. However, in 2009, the Department of Health changed their advice. A summary of their advice (taken from their website) is as follows:
Following a major review of the scientific evidence, the Government has revised its advice to consumers about eating peanuts during pregnancy, breast-feeding and the first few years of life.
This review has shown that there is no clear evidence that eating or not eating peanuts (or foods containing peanuts) during pregnancy, whilst breast-feeding or during early infant life, influences the chances of a child developing a peanut allergy. Therefore, the Government has revised its position and advice is now as follows:
- Pregnancy/breast-feeding. If mothers would like to eat peanuts or foods containing peanuts during pregnancy or whilst breast-feeding, then they can choose to do so as part of a healthy balanced diet, irrespective of whether they have a family history of allergies.
- When introducing peanut into the child's diet. If mothers choose to start giving their baby solid foods before 6 months (after talking to a health visitor or GP), they should not introduce peanuts or other allergens such as nuts, seeds, milk, eggs, wheat, fish or shellfish before this time. Furthermore, when these foods are introduced, they should be introduced one at a time so that they can spot any allergic reaction.
- Where a child has already been diagnosed with another kind of allergy (eg eczema or an allergy to foods other than peanut), or if there is a history of allergy in the child's family. Mothers are encouraged to talk to their GP, health visitor or medical allergy specialist before giving peanut to the child for the first time, because they are at higher risk of developing peanut allergy.
Anything else I need to know?
Some people with peanut allergy might also react to some vegetables (legumes) like soya, green beans, kidney beans, baked beans and green peas because these foods contain similar allergens to peanuts. Be aware that alcohol can make an allergic reaction stronger.
Will it happen again?
Once you have had one allergic reaction, you are very likely to have another because it is impossible always to avoid nuts. This can be stressful to live with. However, if you are well prepared and take action quickly, the risk of suffering any serious problems is small.
Further help & information
Further reading & references
- Wrobel JP, O'Hehir RE, Douglass JA; Food allergy in adults. Aust Fam Physician. 2008 Apr;37(4):222-6.
- Bindslev-Jensen C; ABC of allergies: Food allergy. BMJ 1998 316:1299-1302.
- Consumption of peanut during pregnancy, breastfeeding, and early life and development of peanut allergy; Dept of Health, last modified 25 August 2009; Revised Government advice
- Al-Muhsen S, Clarke A, Kagan R. Peanut Allergy: an overview. Canadian Medical Journal 2003; 168 (10): 1279 - 1285
- Sampson H. Update on Food Allergy. Journal of Allergy and Clinical Immunology 2004; 113 (5): 805-819
- Blumchen K, Ulbricht H, Staden U, et al; Oral peanut immunotherapy in children with peanut anaphylaxis. J Allergy Clin Immunol. 2010 Jun 11.
Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. EMIS has used all reasonable care in compiling the information but make no warranty as to its accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. For details see our conditions.
|Original Author: Dr Tim Kenny||Current Version: Dr Tim Kenny||Peer Reviewer: Dr Beverley Kenny|
|Last Checked: 20/04/2012||Document ID: 7194 Version: 3||© EMIS|
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