I'm new to all this but needed some help. My boyfriend of 20 years suffers from sevre depression he has not had a bout of depression since 2006 and has been happy in life since then without any pills. But all of a sudden it has come back with a vengence! He can not function properly, breaksdown crying and was holed up in the bedroom for a month, he was perscribed mirtazapine 30mg and sleeping pills. The 1st 2 weeks they just made him sleepy and dizzy. He has been taking them now for about 2 1/2 months but they do not seem to be helping the depression, he is a well built 18 stone man who its healthy and loves keeping fit. I know from some of the discussion it depends on the weight and the individual but when will they start working to help his depression and bad thoughts?? Can anyone help?