A friend of mine who used to be an engineer after backing home from a business trip to Japan became ill. The first symptoms were back pain, fever and weakness of lower limb. This was diagnosed as Brucellosis, and disk herniation by some.

This presentation progressed to quadriparesis, lower limb paraplegia, urinary and faecal incontinence (or maybe retention), vertigo, inability to speech and many other overlapping neurological symptoms. He was diagnosed with all kind of infectious and neurological diseases including: HIV infection, Brain TB, MS, GBS, transverse myelitis, etc...

Treatments were aimed toward all the possible differential diagnosis: anti TB medication, Corticosteroid therapy, Plasmapheresis, Interferon.

After six month doctors came to this conclusion that the disease is unknown and the there is no definite treatment.

In my mind, there are two strong differential diagnoses:

1) Transverse Myelitis

2) Tropical Spastic Paraplegia

My friend is confined to bed, paralysed, incontinent and depressed; Waiting for time to remedy his ailment.

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